Renal Functional Outcomes in Patients With Angiomyolipomas: Surveillance vs Embolization vs Nephrectomy

To investigate renal functional outcomes of surveillance, embolization, and surgery for angiomyolipomas (AML). Longitudinal data regarding patients with AML were analyzed retrospectively in this 2-center study. Demographic, radiographic, and functional data were tabulated according to treatment type...

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Published in:Urology (Ridgewood, N.J.) N.J.), 2023-03, Vol.173, p.119-126
Main Authors: Mora, Silvia, Derweesh, Ithaar, Meagher, Margaret, Javier-Desloges, Juan, Noyes, Sabrina L., Lane, Brian R.
Format: Article
Language:English
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Summary:To investigate renal functional outcomes of surveillance, embolization, and surgery for angiomyolipomas (AML). Longitudinal data regarding patients with AML were analyzed retrospectively in this 2-center study. Demographic, radiographic, and functional data were tabulated according to treatment type. Primary outcome was change in renal function from diagnosis to within 6 months postdiagnosis (interim) and to latest glomerular filtration rate (GFR) assessment. 318 patients were diagnosed with AMLs; mean follow-up was 6.2 years. 184 patients (57.9%) were managed with surveillance, 30 (9.4%) underwent embolization, and 103 (32.4%) underwent surgery (91 partial nephrectomy; 12 radical nephrectomy). Baseline characteristics, including tumor size, age, and race differed between the 3 groups (P
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2022.12.010