Pure laparoscopic versus open left lateral hepatectomy in pediatric living donor liver transplantation: a review and meta-analysis

• Published in: Hepatology international 2023-12, Vol.17 (6), p.1587-1595
• Main Authors: Sha, Meng, Zong, Zhi-peng, Shen, Chuan, Zhu, Jian-jun, Feng, Ming-xuan, Luo, Yi, Tong, Ying, Xia, Qiang
• Format: Article
• Language: English
• Subjects: Bile; Child; Colorectal Surgery; Complications; Hepatectomy; Hepatectomy - methods; Hepatic artery; Hepatology; Humans; Invasiveness; Laparoscopy; Laparoscopy - adverse effects; Laparoscopy - methods; Leakage; Literature reviews; Liver; Liver transplantation; Liver Transplantation - methods; Living Donors; Medicine; Medicine & Public Health; Meta-analysis; Original Article; Pediatrics; Portal vein; Postoperative; Postoperative Complications - epidemiology; Subgroups; Surgery; Thromboembolism; Thrombosis; Transplantation; Wound infection; Wound Infection - complications
• ISSN: 1936-0533; 1936-0541
• DOI: 10.1007/s12072-022-10471-z

Purpose The meta-analysis was conducted to evaluate the safety and feasibility of pure laparoscopic left lateral hepatectomy in comparison with open approach for pediatric living donor liver transplantation (LDLT). Methods A systemic literature survey was performed by searching the PubMed, EMBASE and Cochrane Library databases for articles that compared pure laparoscopic left lateral living donor hepatectomy (LLDH) and open left lateral living donor hepatectomy (OLDH) by November 2021. Meta-analysis was performed to assess donors’ and recipients’ perioperative outcomes using RevMan 5.3 software. Results A total of five studies involving 432 patients were included in the analysis. The results demonstrated that LLDH group had significantly less blood loss (WMD = −99.28 ml, 95%CI −152.68 to −45.88, p  = 0.0003) and shorter length of hospital stay (WMD = −2.71d, 95%CI −3.78 to −1.64, p