Risk factors and predictors of acute gastrointestinal injury in stroke patients

This prospective study investigates the incidence, risk factors, biological markers, and predictors of acute gastrointestinal injury (AGI) in patients with stroke. The study involved a total of 98 patients with acute cerebrovascular disease were included. According to the ESICM, the definition of AG...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2023-02, Vol.225, p.107566-107566, Article 107566
Main Authors: Yang, Jia-Xin, Han, Yu-Juan, Yang, Miao-Miao, Gao, Cai-Hong, Cao, Jie
Format: Article
Language:English
Subjects:
Acute gastrointestinal injury
Antibiotics
Biological indicators
Biomarkers
Blood diseases
Cardiovascular system
Cell number
Cerebrovascular disease
Cerebrovascular diseases
Classification
Consciousness
Diabetes
Diabetes mellitus
Hospitals
Humans
Intensive care
Intensive Care Units
Lactic acid
Leukocytes (neutrophilic)
Lymphocytes
Medical prognosis
Mortality
Neutrophils
Patients
Pneumonia
Prognosis
Prospective Studies
Regression analysis
Risk Factors
Stroke
Stroke - epidemiology
Survival analysis
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Summary:This prospective study investigates the incidence, risk factors, biological markers, and predictors of acute gastrointestinal injury (AGI) in patients with stroke. The study involved a total of 98 patients with acute cerebrovascular disease were included. According to the ESICM, the definition of AGI in intensive care patients is classified as grade 0, I, II and III. Patients’ demographics, serological indicators (e.g., urea nitrogen, albumin, D-lactate, α-GST, neutrophil count and lymphocyte count), relevant scores (NIHSS score, GCS score, APACHE II score), length of hospital stay as well as the 7-day and 28-day mortality were recorded. In 98 patients, the incidence of AGI was 90.8 %. The APACHE II, NIHSS, GCS and Hs-mGPS scores significantly increased the odds of a higher AGI grade (P 
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2022.107566