Elevation of C-reactive protein during concurrent chemoradiotherapy is a poor predictive factor for head and neck cancer

The prognostic role of pretreatment C-reactive protein (CRP) has been reported for head and neck cancer. However, little is known about the relationship between the changes in CRP levels during treatment and prognosis. This study aimed to investigate the correlation between CRP elevation during conc...

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Bibliographic Details
Published in:Auris, nasus, larynx nasus, larynx, 2023-08, Vol.50 (4), p.601-606
Main Authors: Adachi, Masahiro, Nakayama, Masahiro, Matsumoto, Shin, Shima, Yoshihide, Uemaetomari, Isao, Yoshimura, Tomonori, Onishi, Kayoko, Senarita, Masamitsu, Tabuchi, Keiji
Format: Article
Language:English
Subjects:
C-reactive protein
Concurrent chemoradiotherapy
Head and neck cancer
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Summary:The prognostic role of pretreatment C-reactive protein (CRP) has been reported for head and neck cancer. However, little is known about the relationship between the changes in CRP levels during treatment and prognosis. This study aimed to investigate the correlation between CRP elevation during concurrent chemoradiotherapy (CCRT) and survival outcomes. The medical records of patients with oropharyngeal, hypopharyngeal, and laryngeal cancer treated with CCRT at the University of Tsukuba Hospital and National Hospital Organization Mito Medical Center from April 2014 to December 2019 were retrospectively reviewed. Patients were divided into normal (
ISSN:0385-8146
1879-1476
DOI:10.1016/j.anl.2022.12.014