Fetal-neonatal and maternal outcomes in women with Sjögren syndrome: a population-based registry linkage study

To provide better preconceptional and prenatal counselling to patients with sjögren syndrome (SS). In total, 2 100 143 pregnancies between 2004 and 2014 were identified in the Taiwan National Health Insurance database and birth registry. The maternal history of SS was ascertained, and data were comp...

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Published in:Rheumatology (Oxford, England) England), 2023-08, Vol.62 (8), p.2820-2828
Main Authors: Chan, Tien-Ming, Wu, Chiao-En, Yu, Han-Hua, Hsiao, Chao-Yang, Su, Tse-Hsuan, Chen, Chun-Bing, Chiou, Meng-Jiung, Yu, Kuang-Hui, Kuo, Chang-Fu
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Language:English
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Summary:To provide better preconceptional and prenatal counselling to patients with sjögren syndrome (SS). In total, 2 100 143 pregnancies between 2004 and 2014 were identified in the Taiwan National Health Insurance database and birth registry. The maternal history of SS was ascertained, and data were compared between pregnant women with and without SS. We assessed the odds ratios and 95% CIs of fetal-neonatal and maternal outcomes. There were 449 pregnancies in women with SS and 2 099 694 pregnancies in women without SS. The risks of still birth [odds ratio (OR) = 2.14, 95% CI = 1.01, 4.55], low birth weight (
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/keac711