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Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis
Objectives To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms. Data Source MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library. Review Methods A systematic review and meta‐an...
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| Published in: | The Laryngoscope 2023-08, Vol.133 (8), p.1806-1814 |
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| Main Authors: | , , , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393 |
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| cites | cdi_FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393 |
| container_end_page | 1814 |
| container_issue | 8 |
| container_start_page | 1806 |
| container_title | The Laryngoscope |
| container_volume | 133 |
| creator | Suppah, Mustafa Kamal, Abdallah Karle, William E. Saadoun, Rakan Lott, David G. |
| description | Objectives
To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms.
Data Source
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
Review Methods
A systematic review and meta‐analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early‐stage glottic neoplasms.
Results
Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP were 90.7% (95% CI 85%–96.5%) and 98.5% (95% CI 97.3%–99.8%), respectively. In the single‐arm meta‐analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%–12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single‐arm meta‐analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one‐year follow‐up, respectively.
Conclusion
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806–1814, 2023
The aim of our review is to evaluate the safety and efficiency of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms. Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP. KTP is a safe and effective method for treating patients with early glottic neoplasms. |
| doi_str_mv | 10.1002/lary.30547 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2761986426</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2761986426</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393</originalsourceid><addsrcrecordid>eNp90MtKxDAYhuEgio6jGy9AAm5E6Jg0h7buyuAJqyOjgoJQ0vQfqKTN2LTK7LwEr9ErsWPVhQtXgeThI7wI7VAyooT4h0bVixEjggcraEAFox6PIrGKBt0j80Lh32-gTeeeCKEBE2QdbTApiZQBHaDHSdtoW4LDdoYvbq9xohzUOM6Magpb4aLCp8Y2TaHxFdi5Ua50RzjGNwvXQKmW91N4KeAVqyrHl9Coj7f3uFJm4Qq3hdZmyjjY_j6H6O7k-HZ85iWT0_NxnHiaiSDwuM4JV4JmmmeRoiqKwkAKX0tKgec-EMYloyRTWvMwJMBDISVVWa4ZUYxFbIj2-915bZ9bcE1aFk6DMaoC27rUDySNQsl92dG9P_TJtnX3306FTIREBoR26qBXurbO1TBL53VRdplTStJl83TZPP1q3uHd78k2KyH_pT-RO0B78FoYWPwzlSbx9KEf_QTKJost</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2835806701</pqid></control><display><type>article</type><title>Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis</title><source>Wiley</source><creator>Suppah, Mustafa ; Kamal, Abdallah ; Karle, William E. ; Saadoun, Rakan ; Lott, David G.</creator><creatorcontrib>Suppah, Mustafa ; Kamal, Abdallah ; Karle, William E. ; Saadoun, Rakan ; Lott, David G.</creatorcontrib><description>Objectives
To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms.
Data Source
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
Review Methods
A systematic review and meta‐analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early‐stage glottic neoplasms.
Results
Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP were 90.7% (95% CI 85%–96.5%) and 98.5% (95% CI 97.3%–99.8%), respectively. In the single‐arm meta‐analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%–12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single‐arm meta‐analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one‐year follow‐up, respectively.
Conclusion
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806–1814, 2023
The aim of our review is to evaluate the safety and efficiency of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms. Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP. KTP is a safe and effective method for treating patients with early glottic neoplasms.</description><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 1531-4995</identifier><identifier>DOI: 10.1002/lary.30547</identifier><identifier>PMID: 36606671</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Ablation ; Glottic cancer ; Glottis - surgery ; Humans ; Laryngeal Neoplasms - surgery ; Laryngoscopy ; Laser Therapy - methods ; Lasers ; Meta-analysis ; Microsurgery - methods ; potassium‐titanyl‐phosphate laser ; recurrence ; Retrospective Studies ; Systematic review ; Tongue Neoplasms - surgery ; transoral laser microsurgery ; Treatment Outcome ; Tumors ; Voice Quality</subject><ispartof>The Laryngoscope, 2023-08, Vol.133 (8), p.1806-1814</ispartof><rights>2023 The American Laryngological, Rhinological and Otological Society, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393</citedby><cites>FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393</cites><orcidid>0000-0001-8585-0781 ; 0000-0003-1867-4831 ; 0000-0001-6541-9687</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36606671$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Suppah, Mustafa</creatorcontrib><creatorcontrib>Kamal, Abdallah</creatorcontrib><creatorcontrib>Karle, William E.</creatorcontrib><creatorcontrib>Saadoun, Rakan</creatorcontrib><creatorcontrib>Lott, David G.</creatorcontrib><title>Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis</title><title>The Laryngoscope</title><addtitle>Laryngoscope</addtitle><description>Objectives
To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms.
Data Source
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
Review Methods
A systematic review and meta‐analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early‐stage glottic neoplasms.
Results
Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP were 90.7% (95% CI 85%–96.5%) and 98.5% (95% CI 97.3%–99.8%), respectively. In the single‐arm meta‐analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%–12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single‐arm meta‐analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one‐year follow‐up, respectively.
Conclusion
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806–1814, 2023
The aim of our review is to evaluate the safety and efficiency of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms. Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP. KTP is a safe and effective method for treating patients with early glottic neoplasms.</description><subject>Ablation</subject><subject>Glottic cancer</subject><subject>Glottis - surgery</subject><subject>Humans</subject><subject>Laryngeal Neoplasms - surgery</subject><subject>Laryngoscopy</subject><subject>Laser Therapy - methods</subject><subject>Lasers</subject><subject>Meta-analysis</subject><subject>Microsurgery - methods</subject><subject>potassium‐titanyl‐phosphate laser</subject><subject>recurrence</subject><subject>Retrospective Studies</subject><subject>Systematic review</subject><subject>Tongue Neoplasms - surgery</subject><subject>transoral laser microsurgery</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><subject>Voice Quality</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp90MtKxDAYhuEgio6jGy9AAm5E6Jg0h7buyuAJqyOjgoJQ0vQfqKTN2LTK7LwEr9ErsWPVhQtXgeThI7wI7VAyooT4h0bVixEjggcraEAFox6PIrGKBt0j80Lh32-gTeeeCKEBE2QdbTApiZQBHaDHSdtoW4LDdoYvbq9xohzUOM6Magpb4aLCp8Y2TaHxFdi5Ua50RzjGNwvXQKmW91N4KeAVqyrHl9Coj7f3uFJm4Qq3hdZmyjjY_j6H6O7k-HZ85iWT0_NxnHiaiSDwuM4JV4JmmmeRoiqKwkAKX0tKgec-EMYloyRTWvMwJMBDISVVWa4ZUYxFbIj2-915bZ9bcE1aFk6DMaoC27rUDySNQsl92dG9P_TJtnX3306FTIREBoR26qBXurbO1TBL53VRdplTStJl83TZPP1q3uHd78k2KyH_pT-RO0B78FoYWPwzlSbx9KEf_QTKJost</recordid><startdate>202308</startdate><enddate>202308</enddate><creator>Suppah, Mustafa</creator><creator>Kamal, Abdallah</creator><creator>Karle, William E.</creator><creator>Saadoun, Rakan</creator><creator>Lott, David G.</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8585-0781</orcidid><orcidid>https://orcid.org/0000-0003-1867-4831</orcidid><orcidid>https://orcid.org/0000-0001-6541-9687</orcidid></search><sort><creationdate>202308</creationdate><title>Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis</title><author>Suppah, Mustafa ; Kamal, Abdallah ; Karle, William E. ; Saadoun, Rakan ; Lott, David G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3577-4cd04a51bc4b9a1a9987652c611e4d2e0346310bacc4880e485661abdc30a3393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Ablation</topic><topic>Glottic cancer</topic><topic>Glottis - surgery</topic><topic>Humans</topic><topic>Laryngeal Neoplasms - surgery</topic><topic>Laryngoscopy</topic><topic>Laser Therapy - methods</topic><topic>Lasers</topic><topic>Meta-analysis</topic><topic>Microsurgery - methods</topic><topic>potassium‐titanyl‐phosphate laser</topic><topic>recurrence</topic><topic>Retrospective Studies</topic><topic>Systematic review</topic><topic>Tongue Neoplasms - surgery</topic><topic>transoral laser microsurgery</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><topic>Voice Quality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Suppah, Mustafa</creatorcontrib><creatorcontrib>Kamal, Abdallah</creatorcontrib><creatorcontrib>Karle, William E.</creatorcontrib><creatorcontrib>Saadoun, Rakan</creatorcontrib><creatorcontrib>Lott, David G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The Laryngoscope</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suppah, Mustafa</au><au>Kamal, Abdallah</au><au>Karle, William E.</au><au>Saadoun, Rakan</au><au>Lott, David G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis</atitle><jtitle>The Laryngoscope</jtitle><addtitle>Laryngoscope</addtitle><date>2023-08</date><risdate>2023</risdate><volume>133</volume><issue>8</issue><spage>1806</spage><epage>1814</epage><pages>1806-1814</pages><issn>0023-852X</issn><eissn>1531-4995</eissn><abstract>Objectives
To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms.
Data Source
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
Review Methods
A systematic review and meta‐analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early‐stage glottic neoplasms.
Results
Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP were 90.7% (95% CI 85%–96.5%) and 98.5% (95% CI 97.3%–99.8%), respectively. In the single‐arm meta‐analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%–12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single‐arm meta‐analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one‐year follow‐up, respectively.
Conclusion
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806–1814, 2023
The aim of our review is to evaluate the safety and efficiency of transoral laser microsurgery (TLM) with potassium‐titanyl‐phosphate (KTP) laser ablation for glottic neoplasms. Eight studies were included. After an average follow‐up of 3.3 years, the overall survival and disease‐free survival for patients who underwent KTP. KTP is a safe and effective method for treating patients with early glottic neoplasms.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>36606671</pmid><doi>10.1002/lary.30547</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-8585-0781</orcidid><orcidid>https://orcid.org/0000-0003-1867-4831</orcidid><orcidid>https://orcid.org/0000-0001-6541-9687</orcidid></addata></record> |
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| identifier | ISSN: 0023-852X |
| ispartof | The Laryngoscope, 2023-08, Vol.133 (8), p.1806-1814 |
| issn | 0023-852X 1531-4995 |
| language | eng |
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| source | Wiley |
| subjects | Ablation Glottic cancer Glottis - surgery Humans Laryngeal Neoplasms - surgery Laryngoscopy Laser Therapy - methods Lasers Meta-analysis Microsurgery - methods potassium‐titanyl‐phosphate laser recurrence Retrospective Studies Systematic review Tongue Neoplasms - surgery transoral laser microsurgery Treatment Outcome Tumors Voice Quality |
| title | Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta‐Analysis |
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