Determinants of Seattle Angina Questionnaire in Multivessel Disease Patients Undergoing Percutaneous Coronary Intervention: Insights from a Single-Center Study

• Published in: Cardiovascular revascularization medicine 2023-04, Vol.49, p.28-33
• Main Authors: Iruvanti, Suvruta, Blumfield, Amit, Farhan, Serdar, Snyder, Clayton, Johal, Gurpreet, Sartori, Samantha, Vogel, Birgit, Giustino, Gennaro, Melarcode-Krishnamoorthy, Parasuram, Kyaw, Htoo, Dangas, George, Mehran, Roxana, Kini, Annapoorna, Sharma, Samin K.
• Format: Article
• Language: English
• Subjects: Angina Pectoris - surgery; Angina Pectoris - therapy; Comorbidities; Coronary Artery Bypass - adverse effects; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - surgery; Female; Humans; Percutaneous Coronary Intervention - adverse effects; Quality of Life; SAQ; Social determinants; Surveys and Questionnaires; Treatment Outcome
• ISSN: 1553-8389; 1878-0938
• DOI: 10.1016/j.carrev.2022.12.012

The Seattle Angina Questionnaire (SAQ-7) quantifies the impact of angina on patient functionality and quality of life. There is scarce data on the impact of social determinants and comorbidities on SAQ-7 in patients undergoing percutaneous coronary intervention (PCI) with planned staged PCI. Patients completed a SAQ-7 before each PCI. Multivariable regression analysis was performed to study the impact of social determinants, comorbidities, and procedural characteristics on SAQ-7 scores at index PCI and at the time of the staged PCI. 531 patients were studied. Female sex, non-White race, coronary artery bypass graft history (CABG), and chronic lung disease were associated with lower baseline SAQ-7 scores. Overall, SAQ-7 increased between index procedure and staged PCI (11.9 ± 23.4). Body mass index (BMI) and the treatment of bifurcation lesions were independently associated with improvement of SAQ-7 between PCIs. Post-intervention, neither sex nor race was independently associated with changes in SAQ-7 scores. Different disparities and comorbid factors affect SAQ-7 before and after PCI. After revascularization, sex and race were not independent predictors of SAQ-7 improvement. [Display omitted] •Different disparities and comorbid factors affect SAQ-7 before and after PCI.•Intervention of birfurcation lesions resulted in higher likelihood of improvement of the SAQ-7 score at the time of staged intervention.•After revascularization, sex and race were not independent predictors of SAQ-7 improvement.