Predictive Factors for the Prognosis of Vogt-Koyanagi-Harada Disease

To identify the prognostic factors in Vogt-Koyanagi-Harada (VKH) disease. This study included 23 patients (46 eyes) with acute-phase VKHdivided into two subgroups: Group 1; acute-resolved (10 patients), group 2; chronic-recurrent (13 patients). Mean age were 29.5 ± 10.2 years in group 1, 35.8 ± 12.2...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2023-09, Vol.ahead-of-print (ahead-of-print), p.1-7
Main Authors: Kaya, Pınar, İnanç Tekin, Merve, Özdal, Pınar Çakar
Format: Article
Language:English
Subjects:
Optical coherence tomography
predictive factor
prognosis
uveitis
Vogt-Koyanagi-Harada disease
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Summary:To identify the prognostic factors in Vogt-Koyanagi-Harada (VKH) disease. This study included 23 patients (46 eyes) with acute-phase VKHdivided into two subgroups: Group 1; acute-resolved (10 patients), group 2; chronic-recurrent (13 patients). Mean age were 29.5 ± 10.2 years in group 1, 35.8 ± 12.2 years group 2 (p = .033). Best-corrected visual acuity with logMAR at admission was 0.91 ± 0.65 in group 1, 0.88 ± 0.62 in group 2 (p = .798), and improved to 0.08 ± 0.24, 0.18 ± 0.6, respectively (p = .557). Extraocular findings were detected in 30% in group 1, and 53.8% in group 2 at the time of admission (p = .108). All patients were treated with 1 g/day 3-5 days intravenous steroid, and 10 patients had immunomodulatory treatment. Initiation of immunomodulatory therapy did not affect the prognosis (p = .676). Older patients and/or who developed extraocular findings at the presentation were more prone to show recurrences.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2022.2159841