Bacteria-based bioactive materials for cancer imaging and therapy

The recent development of bacteria-based bioactive materials in tumor research is reviewed systemically and comprehensively, including general construction strategies of bacteria-based bioactive materials and bacteria-based bioactive material-mediated tumor imaging and therapy. [Display omitted] Owi...

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Bibliographic Details
Published in:Advanced drug delivery reviews 2023-02, Vol.193, p.114696-114696, Article 114696
Main Authors: Chen, Ying, Li, Zi-Hao, Zeng, Xuan, Zhang, Xian-Zheng
Format: Article
Language:English
Subjects:
Bacteria
Bioactive material
Biohybrid
Cancer imaging
Cancer therapy
Diagnostic Imaging
Humans
Nanotechnology - methods
Neoplasms
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Summary:The recent development of bacteria-based bioactive materials in tumor research is reviewed systemically and comprehensively, including general construction strategies of bacteria-based bioactive materials and bacteria-based bioactive material-mediated tumor imaging and therapy. [Display omitted] Owing to the unique biological functions, bacteria as biological materials have been widely used in biomedical field. With advances in biotechnology and nanotechnology, various bacteria-based bioactive materials were developed for cancer imaging and therapy. In this review, different types of bacteria-based bioactive materials and their construction strategies were summarized. The advantages and property-function relationship of bacteria-based bioactive materials were described. Representative researches of bacteria-based bioactive materials in cancer imaging and therapy were illustrated, revealing general ideas for their construction. Also, limitation and challenges of bacteria-based bioactive materials in cancer research were discussed.
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2023.114696