Feasibility of Minimal Enteral Nutrition During Therapeutic Hypothermia for Perinatal Asphyxia: A Five-Year Multicenter Experience from South India

Limited evidence shows minimal enteral nutrition (MEN) during therapeutic hypothermia (TH) in neonates to be feasible and have benefits of shorter time to full-feeds. This study aimed to assess the feasibility of MEN during TH. MEN was initiated after 12 h if there were no altered aspirates, abdomin...

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Published in:Indian journal of pediatrics 2023-05, Vol.90 (5), p.513-515
Main Authors: Sharma, Sunil, Kallesh, Anil, Aradhya, Abhishek Somasekhara, Diggikar, Shivashankar, Veeraiah, Prashanth S., Subbareddy, Narendra N., Walikar, Suvarna, Reddy, I. Venugopal, Sarji, Dhananjaya, Venkatagiri, Praveen
Format: Article
Language:English
Subjects:
Asphyxia
Clinical Brief
Enteral Nutrition
Enterocolitis, Necrotizing
Feasibility Studies
Female
Gynecology
Humans
Hypothermia, Induced
India
Infant, Newborn
Medicine
Medicine & Public Health
Pediatrics
Pregnancy
Retrospective Studies
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Summary:Limited evidence shows minimal enteral nutrition (MEN) during therapeutic hypothermia (TH) in neonates to be feasible and have benefits of shorter time to full-feeds. This study aimed to assess the feasibility of MEN during TH. MEN was initiated after 12 h if there were no altered aspirates, abdominal distension, and inotrope requirement. The authors retrospectively analyzed the records from May 2017 to April 2022. The number of episodes of feed intolerance and the length of hospital stay were the key outcomes. A total of 99 neonates were fed during cooling. MEN could be initiated at a median duration (IQR) of 24 (24–30) h. There were 9 (9%) neonates with feed intolerance during TH. None had necrotizing enterocolitis. Ninety-two (93%) neonates were discharged, with a median hospital stay (IQR) of 9 d (6–15). Hence, MEN during TH is feasible and provides a rationale for future controlled trials.
ISSN:0019-5456
0973-7693
DOI:10.1007/s12098-022-04456-x