Optimal mode of operation for biomass production

The rate of biomass production is optimised for a predefined feed exhaustion using the residue ratio as a degree of freedom. Three modes of operation are considered: continuous, repeated batch, and repeated fed-batch operation. By means of the Production Curve, the transition points of the optimal m...

Full description

Saved in:
Bibliographic Details
Published in:Chemical engineering science 2002-07, Vol.57 (14), p.2799-2809
Main Authors: Betlem, Ben H.L, Mulder, Pieter, Roffel, Brian
Format: Article
Language:English
Subjects:
Batch operation
Biological and medical sciences
Bioreactor
Bioreactors
Biotechnology
Cyclic operation
Fed-batch operation
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Optimal operation
Repeated operation
Various methods and equipments
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The rate of biomass production is optimised for a predefined feed exhaustion using the residue ratio as a degree of freedom. Three modes of operation are considered: continuous, repeated batch, and repeated fed-batch operation. By means of the Production Curve, the transition points of the optimal modes of operation are derived. The analytical expressions of these transitions for variable bioreaction kinetic parameters are determined. The key measures “degree of difficulty of conversion” and “degree of exhaustion” are introduced to define the optimal modes in more general terms. The “degree of difficulty” describes the effect of the kinetic parameters and the feed substrate concentration on the conversion; the “degree of exhaustion” describes the desired final condition. In fed-batch operation, the proposed constant feed policy approximates the optimal feed policy closely.
ISSN:0009-2509
1873-4405
DOI:10.1016/S0009-2509(02)00149-5