Pyrolyzed Ultrasharp Glassy Carbon Microneedles

Glassy carbon microneedles are pyrolyzed from polymeric microneedles that are synthesized by two‐photon polymerization lithography as described in the article number 2201222 by Jeffrey W. Kysar and co‐workers. They enable precise and controlled perforation of a guinea pig’s round window membrane tha...

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Bibliographic Details
Published in:Advanced engineering materials 2022-11, Vol.24 (11), p.n/a
Main Authors: Zhou, Chaoqun, Aksit, Aykut, Szeto, Betsy, Li, Richard L., Lalwani, Anil K., Kysar, Jeffrey W.
Format: Article
Language:English
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Summary:Glassy carbon microneedles are pyrolyzed from polymeric microneedles that are synthesized by two‐photon polymerization lithography as described in the article number 2201222 by Jeffrey W. Kysar and co‐workers. They enable precise and controlled perforation of a guinea pig’s round window membrane that separates the middle ear and inner ear spaces. The perforations open a potential pathway for the delivery of therapeutics into the inner ear to treat hearing and balance disorders.
ISSN:1438-1656
1527-2648
DOI:10.1002/adem.202270046