An intelligent intestinal bleeding diagnosis and treatment capsule system based on color recognition

To our best knowledge, there are no non-invasive and painless means for the diagnosis and treatment of intestinal bleeding as of now, especially the segment of intestine that cannot be reached by endoscopy. We proposed an intelligent intestinal bleeding diagnosis and treatment capsule (IBDTC) system...

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Bibliographic Details
Published in:Biomedical microdevices 2023-03, Vol.25 (1), p.6-6, Article 6
Main Authors: Qiao, Panpan, Yu, Luo, Liu, Hongying, Yan, Xueping, Pi, Xitian
Format: Article
Language:English
Subjects:
Biological and Medical Physics
Biomedical Engineering and Bioengineering
Biophysics
Bleeding
Capsule Endoscopy
Charcoal
Color
Critical components
Detonation
Diagnosis
Endoscopy
Engineering
Engineering Fluid Dynamics
Gastrointestinal Hemorrhage - diagnosis
Gastrointestinal Hemorrhage - therapy
Humans
Intelligence
Intestine
Medical diagnosis
Microelectromechanical systems
Nanotechnology
Pain
Potassium
Potassium nitrate
Power consumption
Reproducibility of Results
Saturation (color)
Small intestine
Sulfur
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Summary:To our best knowledge, there are no non-invasive and painless means for the diagnosis and treatment of intestinal bleeding as of now, especially the segment of intestine that cannot be reached by endoscopy. We proposed an intelligent intestinal bleeding diagnosis and treatment capsule (IBDTC) system for the first time to diagnose and treat intestinal bleeding with low power consumption, estimated to be about 2.16mW. A hue-saturation-light (HSL) color space method was applied to diagnose bleeding according to H (hue) values of the film dyed by blood. A MEMS-based micro-igniter works as the critical component of the micro-thruster that houses the propellant (74.6% potassium nitrate, 11.9% sulfur, 13.5% charcoal) and the detonating agent (dinitrodiazophenol), to help release drug. Bleeding detection and ignition tests were performed to justify its feasibility and reliability. Results demonstrated that the bleeding diagnosis module of the IBDTC can effectively detect bleeding and the micro-igniter can successfully ignite the propellant. Owing to its simplicity and intelligence, the IBDTC system will pave a way for future accurate treatment of small intestinal bleeding with no injury, no pain, no complicated supporting equipment, no need for in vitro operation and positioning.
ISSN:1387-2176
1572-8781
DOI:10.1007/s10544-022-00642-y