Long‐term impact of weight loss for people with overweight but not obesity, and with type 2 diabetes: 10‐year outcomes of a randomized trial of gastric band surgery

• Published in: Diabetes, obesity & metabolism obesity & metabolism, 2023-06, Vol.25 (6), p.1464-1472
• Main Authors: Qi, Qi Yang Damien, Playfair, Julie, Brown, Wendy A., Burton, Paul, O'Brien, Paul E., Wentworth, John M.
• Format: Article
• Language: English
• Subjects: adjustable gastric band; Adult; Bariatric Surgery; Body weight; Body weight loss; Cardiovascular diseases; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - therapy; diabetes remission; Gastrointestinal surgery; Glucose; Glycated Hemoglobin; Hemoglobin; Humans; Obesity; Obesity - complications; Obesity - epidemiology; Obesity - surgery; Overweight; Overweight - complications; Overweight - therapy; Quality of Life; Remission; Remission (Medicine); Surgery; Treatment Outcome; type 2 diabetes; Weight control; Weight Loss
• ISSN: 1462-8902; 1463-1326
• DOI: 10.1111/dom.14992

Aim Randomized trials reporting 5‐year outcomes have shown bariatric surgery  to induce diabetes remission and improve cardiovascular risk. However, the longer‐term effects of surgery are uncertain, with only one randomized trial reporting 10‐year diabetes outcomes in people with obesity. We aimed to compare 10‐year diabetes outcomes of people who are overweight but not obese, randomly assigned to receive either multidisciplinary diabetes care, or multidisciplinary diabetes care combined with gastric band (GB) surgery. Methods Between 2009 and 2011, 51 adults were randomized. After 5 years, they were discharged to receive community care and reassessed after 10 years. The primary outcome was diabetes remission, defined as glycated haemoglobin (HbA1c)