Nanotechnology impacting probiotics and prebiotics: a paradigm shift in nutraceuticals technology

• Published in: International journal of food microbiology 2023-03, Vol.388, p.110083-110083, Article 110083
• Main Authors: Dangi, Priya, Chaudhary, Nisha, Chaudhary, Vandana, Virdi, Amardeep Singh, Kajla, Priyanka, Khanna, Preeti, Jha, Saurabh Kumar, Jha, Niraj Kumar, Alkhanani, Mustfa F., Singh, Vineeta, Haque, Shafiul
• Format: Article
• Language: English
• Subjects: Diet; Food safety; Nanoparticles; Nanoprebiotics; Nanoprobiotics; Nanosynbiotics; Nanotechnology; Prebiotics; Probiotics - metabolism; Synbiotics
• ISSN: 0168-1605; 1879-3460
• DOI: 10.1016/j.ijfoodmicro.2022.110083

This is proven for a long that the incorporation of probiotics and prebiotics in diet exhibits beneficial effects on intestinal and intrinsic health. Nevertheless, this may encounter loss of vitality all along the absorption in the gastrointestinal tract, leading to meager intestinal delivery of probiotic active ingredients. In recent times, nanotechnology has been passionately used to escalate the bioavailability of active ingredients. Versatile forms of nanoparticles (NPs) are devised to be used with probiotics/prebiotics/synbiotics or their different combinations. The NPs currently in trend are constituted of distinctive organic compounds like carbohydrates, proteins, fats, or inorganics such as oxides of silver and titanium or magnesium etc. This review critically explicates the emerging relationship of nanotechnology with probiotics and prebiotics for different applications in neutraceuticals. Here in this review, formulations of nanoprobiotics and nanoprebiotics are discussed in detail, which behave as an effective drug delivery system. In addition, these formulations exhibit anti-cancerous, anti-microbial, anti-oxidant and photo-protective properties. Limited availability of scientific research on nanotechnology concerning probiotics and prebiotics implies dynamic research studies on the bioavailability of loaded active ingredients and the effective drug delivery system by including the safety issues of food and the environment. [Display omitted] •Probiotics & prebiotics in diet exhibit beneficial effects•Pro/prebiotics may suffer absorption in GI and minor intestinal delivery.•Nanotechnology has escalated the bioavailability of active ingredients.•Nanoparticles have been used with probiotics/prebiotics/synbiotics.•We have reviewed the impact of nanotechnology in pro/pre-biotics.