The Association between Placental Abruption and Platelet Indices

• Published in: Fetal and pediatric pathology 2023-05, Vol.42 (3), p.367-375
• Main Authors: Tugrul Ersak, Duygu, Kara, Özgür, Yakut, Kadriye, Tokmak, Aytekin, Sanhal, Cem Yaşar, Yücel, Aykan, Şahin, Dilek
• Format: Article
• Language: English
• Subjects: Abruptio Placentae - diagnosis; Case-Control Studies; Cesarean Section; Female; Humans; Infant, Newborn; inflammation; Mean Platelet Volume; Placenta; Placental abruption; platelet distribution width; platelet indices; platelet to lymphocyte ratio; Pregnancy
• ISSN: 1551-3815; 1551-3823
• DOI: 10.1080/15513815.2023.2166798

Objective: Placental abruption (PA) is an obstetric emergency. This study investigated the use of platelet indices in PA in its early stages to determine if it could aid in diagnosis. Materials and Methods: Sixty-two pregnant women with PA and 130 pregnant women who delivered due to idiopathic preterm delivery were included in this case-control study. Blood samples including platelet indices, biochemical, and coagulation parameters were obtained before cesarean section. Maternal and neonatal outcomes were recorded. Results: There was no significant difference between the groups as to hemoglobin, hematocrit, and white blood count. Platelet, mean platelet volume (MPV), and platelet to lymphocyte ratio (PLR) were significantly lower, platelet distribution width (PDW) was significantly higher in the PA patients. Conclusion: In the current study, MPV and PLR were lower and PDW was higher in PA patients. These parameters may be useful in assessment of PA.