High-intensity interval training improves the outcomes of patients with chronic obstructive pulmonary disease: A meta-analysis of randomized controlled trials

• Published in: Respiratory medicine 2023-03, Vol.208, p.107128-107128, Article 107128
• Main Authors: Wang, Hongyan, Liu, Qin, Liu, Linfeng, Cao, Jun, Liang, Qingfang, Zhang, Xiangeng
• Format: Article
• Language: English
• Subjects: Care; Chronic obstructive pulmonary disease; Exercise; High-Intensity Interval Training; Humans; Lung; Pulmonary Disease, Chronic Obstructive; Quality of Life; Randomized Controlled Trials as Topic; Treatment
• ISSN: 0954-6111; 1532-3064
• DOI: 10.1016/j.rmed.2023.107128

Pulmonary exercise is an important part in the treatment of chronic obstructive pulmonary disease (COPD). We aimed to evaluate the effects and safety of high-intensity interval training (HIIT) in patients with COPD, to provide insights to the COPD treatment and care. Two investigators searched PubMed, Medline, Embase, web of Science, Cochrane library, China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu databases up to Sept 15, 2022 for randomized controlled trials (RCTs) on the effects and safety of HIIT for COPD patients. RevMan5.3 software was used for statistical analysis. A total of 20 RCTs involving 962 COPD patients were finally included. 514 patients underwent HIIT interventions. Meta-analysis showed that HIIT increased the peak oxygen consumption (SMD = 0.30, 95%CI:0.14–0.46), peak minute ventilation (SMD = 0.26, 95%CI: 0.05–0.47), peak work rate (SMD = 0.34, 95%CI: 0.17–0.51), 6-min walking distance (SMD = 0.39, 95%CI: 0.23–0.55) in COPD patients (all P