Methylated ZNF582: a therapeutic target in oral cancer

Zinc finger proteins control the transcription of downstream genes that are implicated in migration, invasion, cell death and proliferation. More mechanistic research on ZNF582 is needed to ascertain how this protein's methylation regulates the inflammatory pathway in oral cancer.

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Bibliographic Details
Published in:Epigenomics 2022-11, Vol.14 (22), p.1389-1392
Main Authors: Prasad, Monisha, Veeraraghavan, Vishnu Priya, Jayaraman, Selvaraj
Format: Article
Language:English
Subjects:
DNA Methylation
epigenetics
Humans
Kruppel-Like Transcription Factors - genetics
methylation
Mouth Neoplasms - drug therapy
Mouth Neoplasms - genetics
oral cancer
Paired Box Transcription Factors - genetics
Paired Box Transcription Factors - metabolism
zinc finger proteins
ZNF582
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Description
Summary:Zinc finger proteins control the transcription of downstream genes that are implicated in migration, invasion, cell death and proliferation. More mechanistic research on ZNF582 is needed to ascertain how this protein's methylation regulates the inflammatory pathway in oral cancer.
ISSN:1750-1911
1750-192X
DOI:10.2217/epi-2022-0368