Detection of impaired gas exchange using the 1-minute sit-to-stand test in patients with interstitial lung disease
Although pulmonary function tests (PFTs) are important in patients with interstitial lung disease (ILD), they cannot be easily performed in a primary healthcare setting. This study aimed to examine the usefulness of the difference between pulse oxygen saturation (SpO2) at rest and the lowest SpO2 du...
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Published in: | Respiratory investigation 2023-03, Vol.61 (2), p.186-189 |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Although pulmonary function tests (PFTs) are important in patients with interstitial lung disease (ILD), they cannot be easily performed in a primary healthcare setting. This study aimed to examine the usefulness of the difference between pulse oxygen saturation (SpO2) at rest and the lowest SpO2 during the 1-min sit-to-stand test (delta SpO2-1STST) for predicting pulmonary function impairment.
We retrospectively reviewed 116 patients with ILD who underwent 1STST and PFTs.
The delta SpO2-1STST and diffusing capacity for carbon monoxide (DLco) strongly correlated (ρ = 0.70). The delta SpO2-1STST was effective in predicting impaired gas exchange (cut-off value, −4%; AUC, 0.86; sensitivity, 74%; specificity, 87%).
The Delta SpO2-1STST may be a reasonable tool for predicting abnormalities in PFTs. |
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ISSN: | 2212-5345 2212-5353 |
DOI: | 10.1016/j.resinv.2022.12.009 |