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Incremental Effect of Mitral Regurgitation on Left Atrial Dysfunction and Atrioventricular Interaction in Hypertensive Patients by MRI

Mitral regurgitation may occur when hypertension causes left ventricular (LV) and left atrial (LA) remodeling. However, its role in LA function in hypertensive patients remains unclear. To explore how mitral regurgitation affects LA function in hypertension and to investigate atrioventricular intera...

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Bibliographic Details
Published in:Journal of magnetic resonance imaging 2023-10, Vol.58 (4), p.1125-1136
Main Authors: Tang, Si-Shi, Shi, Rui, Yang, Zhi-Gang, Wang, Jin, Min, Chen-Yan, Yan, Wei-Feng, Zhang, Yi, Li, Yuan
Format: Article
Language:English
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Summary:Mitral regurgitation may occur when hypertension causes left ventricular (LV) and left atrial (LA) remodeling. However, its role in LA function in hypertensive patients remains unclear. To explore how mitral regurgitation affects LA function in hypertension and to investigate atrioventricular interaction in hypertensive patients with mitral regurgitation. Retrospective. A total of 193 hypertensive cases and 64 controls. A 3.0 T/balanced steady-state free precession. LA volume (LAV), LA strain (reservoir, conduit, and active), LA ejection fraction, and LV strain (global peak longitudinal [GLS], circumferential [GCS], and radial strain [GRS]) were evaluated and compared among groups. Regurgitant fraction (RF) was evaluated in regurgitation patients and used to subdivide patients into mild (RF: 0%-30%), moderate (RF: 30%-50%), and severe (RF: >50%) regurgitation categories. One-way analysis of variance, Spearman and Pearson's correlation coefficients (r), and multivariable linear regression analysis. A P value
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.28604