Association between macular and papillary vessel density by optical coherence tomography angiography in a large healthy population

• Published in: Photodiagnosis and photodynamic therapy 2023-06, Vol.42, p.103324-103324, Article 103324
• Main Authors: Fernández-Vigo, José Ignacio, Burgos-Blasco, Bárbara, De-Pablo-Gómez-de-Liaño, Lucía, Kudsieh, Bachar, Fernández-Vigo, José Ángel, García-Feijóo, Julián
• Format: Article
• Language: English
• Subjects: Macular vessel density; Optic nerve head; Optical coherence tomography angiography; Papillary vessel density; Retinal vasculature
• ISSN: 1572-1000; 1873-1597
• DOI: 10.1016/j.pdpdt.2023.103324

•There is no association between macular and papillary vessel density by OCTA.•No differences in gender or age in the relationship between macular and papillary vasculature.•Macular and papillary vascularization should be investigated separately in each disease. To provide a normative data set of the relationship between macular and papillary vessel density (VD) using swept-source optical coherence tomography angiography (SS-OCTA) in a large healthy population. Cross-sectional study conducted on 346 right eyes of healthy subjects. Macular and papillary SS-OCTA VD measurements of the retinal superficial capillary plexus (SCP), deep capillary plexus (DCP), and choriocapillaris (CC) in the central area and the four quadrants were obtained. Correlations between macular and papillary VD among different quadrants were assessed. The mean participant age was 37.7 ± 19.8 years (range 5–83); 59% were women. No correlation was detected neither for the global SCP (R = 0.050; P = 0.040), DCP (R = -0.056; P = 0.038) nor CC (R = 0.102; P