Burden of Hypertensive Crisis in Patients With End-Stage Kidney Disease on Maintenance Dialysis: Insights From United States Renal Data System Database

• Published in: Hypertension (Dallas, Tex. 1979) Tex. 1979), 2023-04, Vol.80 (4), p.e59-e67
• Main Authors: Pothuru, Suveenkrishna, Chan, Wan-Chi, Mehta, Harsh, Vindhyal, Mohinder R., Ranka, Sagar, Hu, Jinxiang, Yarlagadda, Sri G, Wiley, Mark A., Hockstad, Eric, Tadros, Peter N, Gupta, Kamal
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Female; Hospitalization; Humans; Kidney Failure, Chronic - diagnosis; Kidney Failure, Chronic - epidemiology; Kidney Failure, Chronic - therapy; Male; Patient Readmission; Renal Dialysis - adverse effects; Retrospective Studies; United States - epidemiology
• ISSN: 0194-911X; 1524-4563
• DOI: 10.1161/HYPERTENSIONAHA.122.20546

There is paucity of information on the incidence, clinical characteristics, admission trends, and outcomes of hypertensive crisis (HTN-C) in patients with end-stage kidney disease (ESKD) who are on maintenance dialysis. We conducted a retrospective observational study of HTN-C admissions in patients with end-stage kidney disease using the United States Renal Data System. We identified patients with end-stage kidney disease aged ≥18 years on dialysis and were hospitalized for HTN-C from January 2006 to August 2015. A total of 54 483 patients with end-stage kidney disease were hospitalized for HTN-C during the study period. After study exclusions, 37 214 patients were included in the analysis. A majority of patients were Black, there were more women than men and the South region of the country accounted for a great majority of patients. During the study period, hospitalization rates increased from 1060 per 100 000 beneficiary years to 1821 (