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Meta-Analysis Comparing Outcomes of Remote Hemodynamic Assessment Versus Standard Care in Patients With Heart Failure
In patients with congestive heart failure (CHF), remote hemodynamic monitoring can reduce heart failure exacerbation and mortality. In this study, we compared the effectiveness of remote hemodynamic monitoring with that of standard care in the management of patients with CHF. The remote monitoring g...
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Published in: | The American journal of cardiology 2023-04, Vol.192, p.79-87 |
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creator | Buttar, Chandan Lakhdar, Sofia Nso, Nso Guzman-Perez, Laura Dao, Tristan Mahmood, Kiran Hendel, Robert Lavie, Carl J. Collura, Giovina Trandafirescu, Theo |
description | In patients with congestive heart failure (CHF), remote hemodynamic monitoring can reduce heart failure exacerbation and mortality. In this study, we compared the effectiveness of remote hemodynamic monitoring with that of standard care in the management of patients with CHF. The remote monitoring group included 7,733 patients, and the control group included 7,567 patients. Chi-square test and I-square statistics were used to assess heterogeneity. Risk ratios (RRs) were calculated using fixed-effects and random-effects methods to determine the risk of all-cause hospitalization and CHF-related hospitalization (primary outcomes) and all-cause mortality and device outcomes (secondary outcomes). Pooled findings indicated a 7% lower risk of all-cause hospitalization in the remote monitoring group than that in the control group (RR 0.93, 95% confidence interval [CI] 0.89 to 0.98, p = 0.004). The results also revealed a 32% lower risk of CHF-related hospitalization in the remote monitoring group than that in the control group (RR 0.68, 95% CI 0.65 to 0.71, p |
doi_str_mv | 10.1016/j.amjcard.2022.12.033 |
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In this study, we compared the effectiveness of remote hemodynamic monitoring with that of standard care in the management of patients with CHF. The remote monitoring group included 7,733 patients, and the control group included 7,567 patients. Chi-square test and I-square statistics were used to assess heterogeneity. Risk ratios (RRs) were calculated using fixed-effects and random-effects methods to determine the risk of all-cause hospitalization and CHF-related hospitalization (primary outcomes) and all-cause mortality and device outcomes (secondary outcomes). Pooled findings indicated a 7% lower risk of all-cause hospitalization in the remote monitoring group than that in the control group (RR 0.93, 95% confidence interval [CI] 0.89 to 0.98, p = 0.004). The results also revealed a 32% lower risk of CHF-related hospitalization in the remote monitoring group than that in the control group (RR 0.68, 95% CI 0.65 to 0.71, p <0.001). No statistically significant differences were noted between the groups in terms of all-cause mortality (RR 0.97, 95% CI 0.87 to 1.07, p = 0.53) and device outcomes (RR 1.23 95% CI 0.92 to 1.65, p = 0.16). These results provided evidence regarding the comparable effectiveness of remote CHF monitoring and routine care. The current evidence is insufficient to introduce remote hemodynamic CHF monitoring; however, our results suggest that the integration of telemonitoring systems with routine medical management may improve heart failure care.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2022.12.033</identifier><identifier>PMID: 36758268</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Bias ; Chi-square test ; Cohort analysis ; Congestive heart failure ; Effectiveness ; Heart Failure ; Hemodynamics ; Heterogeneity ; Hospitalization ; Humans ; Meta-analysis ; Monitoring ; Monitoring, Physiologic - methods ; Mortality ; Pulmonary arteries ; Remote monitoring ; Statistical analysis ; Statistical tests ; Systematic review ; Telemedicine ; Variables</subject><ispartof>The American journal of cardiology, 2023-04, Vol.192, p.79-87</ispartof><rights>2023 Elsevier Inc.</rights><rights>Copyright © 2023 Elsevier Inc. All rights reserved.</rights><rights>2023. Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c341t-ecd79b378ce90a73f7f137197fe7aac2ed853e2dd8621354e54a2d7a0d6c55943</cites><orcidid>0000-0001-5320-2990</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36758268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Buttar, Chandan</creatorcontrib><creatorcontrib>Lakhdar, Sofia</creatorcontrib><creatorcontrib>Nso, Nso</creatorcontrib><creatorcontrib>Guzman-Perez, Laura</creatorcontrib><creatorcontrib>Dao, Tristan</creatorcontrib><creatorcontrib>Mahmood, Kiran</creatorcontrib><creatorcontrib>Hendel, Robert</creatorcontrib><creatorcontrib>Lavie, Carl J.</creatorcontrib><creatorcontrib>Collura, Giovina</creatorcontrib><creatorcontrib>Trandafirescu, Theo</creatorcontrib><title>Meta-Analysis Comparing Outcomes of Remote Hemodynamic Assessment Versus Standard Care in Patients With Heart Failure</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>In patients with congestive heart failure (CHF), remote hemodynamic monitoring can reduce heart failure exacerbation and mortality. In this study, we compared the effectiveness of remote hemodynamic monitoring with that of standard care in the management of patients with CHF. The remote monitoring group included 7,733 patients, and the control group included 7,567 patients. Chi-square test and I-square statistics were used to assess heterogeneity. Risk ratios (RRs) were calculated using fixed-effects and random-effects methods to determine the risk of all-cause hospitalization and CHF-related hospitalization (primary outcomes) and all-cause mortality and device outcomes (secondary outcomes). Pooled findings indicated a 7% lower risk of all-cause hospitalization in the remote monitoring group than that in the control group (RR 0.93, 95% confidence interval [CI] 0.89 to 0.98, p = 0.004). The results also revealed a 32% lower risk of CHF-related hospitalization in the remote monitoring group than that in the control group (RR 0.68, 95% CI 0.65 to 0.71, p <0.001). No statistically significant differences were noted between the groups in terms of all-cause mortality (RR 0.97, 95% CI 0.87 to 1.07, p = 0.53) and device outcomes (RR 1.23 95% CI 0.92 to 1.65, p = 0.16). These results provided evidence regarding the comparable effectiveness of remote CHF monitoring and routine care. The current evidence is insufficient to introduce remote hemodynamic CHF monitoring; however, our results suggest that the integration of telemonitoring systems with routine medical management may improve heart failure care.</description><subject>Bias</subject><subject>Chi-square test</subject><subject>Cohort analysis</subject><subject>Congestive heart failure</subject><subject>Effectiveness</subject><subject>Heart Failure</subject><subject>Hemodynamics</subject><subject>Heterogeneity</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Meta-analysis</subject><subject>Monitoring</subject><subject>Monitoring, Physiologic - methods</subject><subject>Mortality</subject><subject>Pulmonary arteries</subject><subject>Remote monitoring</subject><subject>Statistical analysis</subject><subject>Statistical tests</subject><subject>Systematic review</subject><subject>Telemedicine</subject><subject>Variables</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFkc2KFDEUhYMoTjv6CErAjZsqc5NKJbWSpnEcYWTE32XIJLc0Rf30JCmh39403bpw4-oS8p2bcD5CngOrgUH7eqjtNDgbfc0Z5zXwmgnxgGxAq66CDsRDsmGM8aqDprsgT1IayhFAto_JhWiV1LzVG7J-wGyr7WzHQwqJ7pZpb2OYf9DbNbtlwkSXnn7CaclIr8vwh9lOwdFtSpjShHOm3zCmNdHP2c6-_IfubEQaZvrR5lDuE_0e8s8StjHTKxvGNeJT8qi3Y8Jn53lJvl69_bK7rm5u373fbW8qJxrIFTqvujuhtMOOWSV61YNQ0KkelbWOo9dSIPdetxyEbFA2lntlmW-dlF0jLsmr0959XO5XTNlMITkcRzvjsibDlZItiEZDQV_-gw7LGksvR0pL0FoqUSh5olxcUorYm30Mk40HA8wcvZjBnL2YoxcD3BQvJffivH29m9D_Tf0RUYA3JwBLHb8CRpNcac-hDxFdNn4J_3niN4GLoYQ</recordid><startdate>20230401</startdate><enddate>20230401</enddate><creator>Buttar, Chandan</creator><creator>Lakhdar, Sofia</creator><creator>Nso, Nso</creator><creator>Guzman-Perez, Laura</creator><creator>Dao, Tristan</creator><creator>Mahmood, Kiran</creator><creator>Hendel, Robert</creator><creator>Lavie, Carl J.</creator><creator>Collura, Giovina</creator><creator>Trandafirescu, Theo</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5320-2990</orcidid></search><sort><creationdate>20230401</creationdate><title>Meta-Analysis Comparing Outcomes of Remote Hemodynamic Assessment Versus Standard Care in Patients With Heart Failure</title><author>Buttar, Chandan ; 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In this study, we compared the effectiveness of remote hemodynamic monitoring with that of standard care in the management of patients with CHF. The remote monitoring group included 7,733 patients, and the control group included 7,567 patients. Chi-square test and I-square statistics were used to assess heterogeneity. Risk ratios (RRs) were calculated using fixed-effects and random-effects methods to determine the risk of all-cause hospitalization and CHF-related hospitalization (primary outcomes) and all-cause mortality and device outcomes (secondary outcomes). Pooled findings indicated a 7% lower risk of all-cause hospitalization in the remote monitoring group than that in the control group (RR 0.93, 95% confidence interval [CI] 0.89 to 0.98, p = 0.004). The results also revealed a 32% lower risk of CHF-related hospitalization in the remote monitoring group than that in the control group (RR 0.68, 95% CI 0.65 to 0.71, p <0.001). No statistically significant differences were noted between the groups in terms of all-cause mortality (RR 0.97, 95% CI 0.87 to 1.07, p = 0.53) and device outcomes (RR 1.23 95% CI 0.92 to 1.65, p = 0.16). These results provided evidence regarding the comparable effectiveness of remote CHF monitoring and routine care. The current evidence is insufficient to introduce remote hemodynamic CHF monitoring; however, our results suggest that the integration of telemonitoring systems with routine medical management may improve heart failure care.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>36758268</pmid><doi>10.1016/j.amjcard.2022.12.033</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-5320-2990</orcidid></addata></record> |
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subjects | Bias Chi-square test Cohort analysis Congestive heart failure Effectiveness Heart Failure Hemodynamics Heterogeneity Hospitalization Humans Meta-analysis Monitoring Monitoring, Physiologic - methods Mortality Pulmonary arteries Remote monitoring Statistical analysis Statistical tests Systematic review Telemedicine Variables |
title | Meta-Analysis Comparing Outcomes of Remote Hemodynamic Assessment Versus Standard Care in Patients With Heart Failure |
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