Quercetin extraction from small onion skin (Allium cepa L. var. aggregatum Don.) and its antioxidant activity

In the present study, the maximum yield of quercetin was optimized for the ethanol extraction of small onions (Allium cepa L. var. aggregatum Don.), and the antioxidant activity was investigated in vitro. The extraction of quercetin from the small onion skin was carried out through ethanol solvent e...

Full description

Saved in:
Bibliographic Details
Published in:Environmental research 2023-05, Vol.224, p.115497-115497
Main Authors: M Al-Ansari, Mysoon, Al-Humaid, Latifah, Aldawsari, Majdoleen, Abid, Islem Faraj, Jhanani, G K, Shanmuganathan, Rajasree
Format: Article
Language:English
Subjects:
Antioxidants - analysis
Ethanol
Onions
Plant Extracts
Quercetin
Shallots
Water
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the present study, the maximum yield of quercetin was optimized for the ethanol extraction of small onions (Allium cepa L. var. aggregatum Don.), and the antioxidant activity was investigated in vitro. The extraction of quercetin from the small onion skin was carried out through ethanol solvent extraction with different ratios of ethanol and water. Ethanol: water ratio produced the highest quercetin from the onion skin. RP-HPLC analysis of the extracted material showed 2, 122 mg/g of quercetin and 0.34 mg/g of isorhamnetin. A total of 301.03 mg GAE/g dry weight and 156 mg/g quercetin equivalents were found in the onion skin extract. DPPH and ABTS free radical scavenging potentials of the tested extract (90:10 v/v) were dose-dependent, with IC values of 62.27 μg/mL and 53.65 μg/mL, respectively. Therefore, the present study reports that small onion skin extract rich in quercetin may serve as a promising antioxidant and anticancer agent.
ISSN:1096-0953
DOI:10.1016/j.envres.2023.115497