The link between cardiac status and depression and anxiety in implantable cardioverter defibrillator patients: Design and first results of the PSYCHE-ICD study

Depression and anxiety in patients with an implantable cardioverter-defibrillator (ICD) are associated with adverse outcomes. This study describes the design of the PSYCHE-ICD study and evaluates the correlation between cardiac status and depression and anxiety in ICD patients. We included 178 patie...

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Bibliographic Details
Published in:Journal of psychosomatic research 2023-04, Vol.167, p.111182-111182, Article 111182
Main Authors: van der Lingen, Anne-Lotte C.J., Rijnierse, Mischa T., Hooghiemstra, Astrid M., Elshout, Saskia, van Halm, Vokko P., Batelaan, Neeltje M., van Rossum, Albert C., Pedersen, Susanne S., Leeuwis, Anna E., Allaart, Cornelis P.
Format: Article
Language:English
Subjects:
Anxiety
Anxiety - psychology
Autonomic function
Cross-Sectional Studies
Defibrillators, Implantable
Depression
Depression - psychology
Heart failure
Humans
Implantable cardioverter defibrillator
Stroke Volume
Ventricular Function, Left
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Summary:Depression and anxiety in patients with an implantable cardioverter-defibrillator (ICD) are associated with adverse outcomes. This study describes the design of the PSYCHE-ICD study and evaluates the correlation between cardiac status and depression and anxiety in ICD patients. We included 178 patients. Prior to implantation, patients completed validated psychological questionnaires for depression, anxiety and personality traits. Cardiac status was evaluated by means of left ventricular ejection fraction assessment (LVEF), New York Heart Association (NYHA) functional class, 6-minute walk test (6MWT), and 24-h Holter monitoring for heart rate variability (HRV). A cross-sectional analysis was performed. Follow-up with annual study visits, including repeated full cardiac evaluation, will continue 36 months after ICD implantation. Depressive symptoms were present in 62 (35%) and anxiety in 56 (32%) patients. Values of depression and anxiety significantly increased with higher NYHA class (P 
ISSN:0022-3999
1879-1360
DOI:10.1016/j.jpsychores.2023.111182