Antireflux surgery versus medical management of gastro-oesophageal reflux after lung transplantation

Gastro-oesophageal reflux disease after lung transplantation may be associated with chronic lung allograft dysfunction. Aspiration may continue on medical management of reflux, but antireflux surgery potentially reduces all reflux. We compared outcomes between medical and surgical management of refl...

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Bibliographic Details
Published in:European journal of cardio-thoracic surgery 2023-03, Vol.63 (3)
Main Authors: Razia, Deepika, Mittal, Sumeet K, Fournier, Sarah, Walia, Rajat, Smith, Michael A, Bremner, Ross M, Huang, Jasmine L
Format: Article
Language:English
Subjects:
Fundoplication
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - surgery
Hernia, Hiatal - surgery
Humans
Laparoscopy
Lung
Lung Transplantation
Retrospective Studies
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Summary:Gastro-oesophageal reflux disease after lung transplantation may be associated with chronic lung allograft dysfunction. Aspiration may continue on medical management of reflux, but antireflux surgery potentially reduces all reflux. We compared outcomes between medical and surgical management of reflux in lung recipients. Lung recipients with an elevated DeMeester score (≥14.72) on post-transplant reflux testing between 2015 and 2020 were included. Patients were divided into 2 groups: group A (underwent surgery) and group B (medically managed). Endpoints were pulmonary function, allograft dysfunction-free survival and overall survival. Further analysis included subgroups: A1 (early surgery, 6 months), and B1 (DeMeester
ISSN:1873-734X
1873-734X
DOI:10.1093/ejcts/ezad063