Bioactive behaviors of porous apatite- and wollastonite-containing glass-ceramic in two kinds of simulated body fluid

Simulated body fluid (SBF) has been widely used for assessment of bioactivities of different materials. Those kinds of conventional SBF (C-SBF) have a higher Cl− concentration and a lower HCO3− concentration than those of human blood plasma. Therefore, a revised simulated body fluid (R-SBF), with io...

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Bibliographic Details
Published in:Journal of materials research 2003-02, Vol.18 (2), p.433-441
Main Authors: Zhang, Yunlong, Mizuno, Mineo, Yanagisawa, Masaaki, Takadama, Hiroaki
Format: Article
Language:English
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Summary:Simulated body fluid (SBF) has been widely used for assessment of bioactivities of different materials. Those kinds of conventional SBF (C-SBF) have a higher Cl− concentration and a lower HCO3− concentration than those of human blood plasma. Therefore, a revised simulated body fluid (R-SBF), with ion concentrations including those of Cl− and HCO3− exactly equal to those of human plasma, was recently developed. Porous glass-ceramic was used as the testing material to evaluate the two kinds of SBF. Results showed that C-SBF is considered more active than R-SBF because the porous glass-ceramic had a higher apatite formation rate on its surface,while R-SBF is considered to simulate the human body fluid more precisely than C-SBF.
ISSN:0884-2914
2044-5326
DOI:10.1557/JMR.2003.0055