Vaccine hesitancy in cancer patients: A rapid review

• Published in: Patient education and counseling 2023-06, Vol.111, p.107680, Article 107680
• Main Authors: Butow, P., Shaw, J., Bartley, N., Milch, V., Sathiaraj, R., Turnbull, Scott, Der Vartanian, C.
• Format: Article
• Language: English
• Subjects: Cancer patients; COVID-19 - epidemiology; COVID-19 - prevention & control; COVID-19 vaccine hesitancy; COVID-19 Vaccines; Humans; Neoplasms - prevention & control; Pandemics; Vaccination; Vaccination Hesitancy
• ISSN: 0738-3991; 1873-5134; 1873-5134
• DOI: 10.1016/j.pec.2023.107680

Vaccination is a key strategy to limit the impact of the COVID-19 pandemic, among vulnerable groups such as cancer patients. However, COVID-19 vaccine hesitancy is limiting vaccination uptake in this population as in others. This study aimed to synthesise the emerging literature on vaccine hesitancy in this population and in Oncology health professionals, reasons for and factors associated with hesitancy, and interventions that address hesitancy. A rapid review was undertaken PubMed, Ovid and Google across all years up to October 2021 for articles in English, from any country or region, addressing the above issues. Individual case studies, opinion pieces, commentary articles and conference abstracts were excluded. Article screening, data extraction and bias assessment were conducted by two authors. A narrative synthesis of the data was undertaken. Eighteen eligible articles were identified. Reported COVID-19 vaccine hesitancy rates varied from 76.7 % to 3.9 %, with a mean of 38.4 %. A large international study (n > 20,000) reported a more conservative hesitancy rate of 19 %. Six broad, common reasons for hesitancy were identified. Oncologist advice was valued by patients. Vaccine hesitancy remains a significant concern in the oncology context. Oncologists are key to addressing hesitancy and providing tailored advice to cancer patients. Where possible, patients appreciate personalised, tailored information about vaccination which addresses its interaction with cancer and its treatment. Education programmes for oncologists to support effective communication in this context are needed. Webinars and peer-to-peer counselling may be useful but remain to be proven. •Covid-19 vaccination hesitancy rates in cancer patients vary significantly cross-culturally.•A large international study estimated hesitancy rates at 19 %.•Cancer patients have unique concerns about vaccination, including interactions with cancer treatments.•Tailored advice from oncologists about vaccination is highly valued by patients.