Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis

• Published in: International journal of surgery case reports 2023, Vol.104, p.107911-107911
• Main Authors: Komarov, R N, Tkachev, M I, Ismailbaev, A M, Nuzhdin, M D, Savina, V A, Botashev, A A
• Format: Report
• Language: English
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2023.107911

INTRODUCTION AND IMPORTANCEBekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2-10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities. CASE PRESENTATIONIn this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position. CLINICAL DISCUSSIONThe use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves. CONCLUSIONThis clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach.