Realistic expectations are key to realising the benefits of polygenic scores

We must not let enthusiasm around polygenic scores allow us to forget other factors that are bigger, more modifiable, and relevant for everyone, argue Amit Sud, Rachel Horton, and colleagues

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Bibliographic Details
Published in:BMJ (Online) 2023-02, Vol.380, p.e073149
Main Authors: Sud, Amit, Horton, Rachel H, Hingorani, Aroon D, Tzoulaki, Ioanna, Turnbull, Clare, Houlston, Richard S, Lucassen, Anneke
Format: Article
Language:English
Subjects:
Accuracy
Analysis
Antigens
Breast cancer
Cardiovascular disease
Colorectal cancer
Coronary vessels
Disease - genetics
Disease prevention
Genomes
Health risk assessment
Humans
Mammography
Medical screening
Multifactorial Inheritance
Prostate cancer
Risk
Risk factors
Vein & artery diseases
Womens health
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Description
Summary:We must not let enthusiasm around polygenic scores allow us to forget other factors that are bigger, more modifiable, and relevant for everyone, argue Amit Sud, Rachel Horton, and colleagues
ISSN:1756-1833
1756-1833
DOI:10.1136/bmj-2022-073149