Relapsed Synovial Sarcoma: Treatment Options

Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the curr...

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Bibliographic Details
Published in:Current treatment options in oncology 2023-03, Vol.24 (3), p.229-239
Main Authors: Weiss, Mia C., Van Tine, Brian A.
Format: Article
Language:English
Subjects:
Chemotherapy
Clinical trials
Humans
Medicine
Medicine & Public Health
Oncology
Sarcoma
Sarcoma (SH Okuno
Sarcoma, Synovial - diagnosis
Sarcoma, Synovial - therapy
Section Editor
Soft Tissue Neoplasms
Soft tissue sarcoma
Synovial sarcoma
Topical Collection on Sarcoma
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Summary:Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the current standard of care, as well as the current therapies showing promise in a clinical trial. It is our hope that by encouraging participation in clinical trials, the fundamental therapies available for SS will change the current treatment paradigm.
ISSN:1527-2729
1534-6277
1534-5277
DOI:10.1007/s11864-023-01056-5