Loading…

Relapsed Synovial Sarcoma: Treatment Options

Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the curr...

Full description

Saved in:
Bibliographic Details
Published in:Current treatment options in oncology 2023-03, Vol.24 (3), p.229-239
Main Authors: Weiss, Mia C., Van Tine, Brian A.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3
cites cdi_FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3
container_end_page 239
container_issue 3
container_start_page 229
container_title Current treatment options in oncology
container_volume 24
creator Weiss, Mia C.
Van Tine, Brian A.
description Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the current standard of care, as well as the current therapies showing promise in a clinical trial. It is our hope that by encouraging participation in clinical trials, the fundamental therapies available for SS will change the current treatment paradigm.
doi_str_mv 10.1007/s11864-023-01056-5
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2783497646</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2783497646</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3</originalsourceid><addsrcrecordid>eNp9kEtLxDAQx4Mo7vr4Ah6k4MWD0cmjSepNFl-wsOCu55BNU-nSl0kr7Le3tauCB08zML_5z_BD6IzANQGQN4EQJTgGyjAQiAWO99CUxIxjQaXcH3oqMZU0maCjEDYANOaQHKIJE0pIppIpunpxhWmCS6Pltqo_clNES-NtXZrbaOWdaUtXtdGiafO6CifoIDNFcKe7eoxeH-5Xsyc8Xzw-z-7m2DIZt9iATImggiWCpyo2ljAwKec0ziBLFWOGK0LjdJ1YZYUwlDunQGWOgyJWWHaMLsfcxtfvnQutLvNgXVGYytVd0FQqxhMpuOjRiz_opu581X83UJwD6830FB0p6-sQvMt04_PS-K0moAeXenSpe5f6y6Uels530d26dOnPyre8HmAjEPpR9eb87-1_Yj8BWQV8cg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2784403105</pqid></control><display><type>article</type><title>Relapsed Synovial Sarcoma: Treatment Options</title><source>Springer Link</source><creator>Weiss, Mia C. ; Van Tine, Brian A.</creator><creatorcontrib>Weiss, Mia C. ; Van Tine, Brian A.</creatorcontrib><description>Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the current standard of care, as well as the current therapies showing promise in a clinical trial. It is our hope that by encouraging participation in clinical trials, the fundamental therapies available for SS will change the current treatment paradigm.</description><identifier>ISSN: 1527-2729</identifier><identifier>EISSN: 1534-6277</identifier><identifier>EISSN: 1534-5277</identifier><identifier>DOI: 10.1007/s11864-023-01056-5</identifier><identifier>PMID: 36867389</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Chemotherapy ; Clinical trials ; Humans ; Medicine ; Medicine &amp; Public Health ; Oncology ; Sarcoma ; Sarcoma (SH Okuno ; Sarcoma, Synovial - diagnosis ; Sarcoma, Synovial - therapy ; Section Editor ; Soft Tissue Neoplasms ; Soft tissue sarcoma ; Synovial sarcoma ; Topical Collection on Sarcoma</subject><ispartof>Current treatment options in oncology, 2023-03, Vol.24 (3), p.229-239</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3</citedby><cites>FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3</cites><orcidid>0000-0002-8457-0523</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36867389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weiss, Mia C.</creatorcontrib><creatorcontrib>Van Tine, Brian A.</creatorcontrib><title>Relapsed Synovial Sarcoma: Treatment Options</title><title>Current treatment options in oncology</title><addtitle>Curr. Treat. Options in Oncol</addtitle><addtitle>Curr Treat Options Oncol</addtitle><description>Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the current standard of care, as well as the current therapies showing promise in a clinical trial. It is our hope that by encouraging participation in clinical trials, the fundamental therapies available for SS will change the current treatment paradigm.</description><subject>Chemotherapy</subject><subject>Clinical trials</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Oncology</subject><subject>Sarcoma</subject><subject>Sarcoma (SH Okuno</subject><subject>Sarcoma, Synovial - diagnosis</subject><subject>Sarcoma, Synovial - therapy</subject><subject>Section Editor</subject><subject>Soft Tissue Neoplasms</subject><subject>Soft tissue sarcoma</subject><subject>Synovial sarcoma</subject><subject>Topical Collection on Sarcoma</subject><issn>1527-2729</issn><issn>1534-6277</issn><issn>1534-5277</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLxDAQx4Mo7vr4Ah6k4MWD0cmjSepNFl-wsOCu55BNU-nSl0kr7Le3tauCB08zML_5z_BD6IzANQGQN4EQJTgGyjAQiAWO99CUxIxjQaXcH3oqMZU0maCjEDYANOaQHKIJE0pIppIpunpxhWmCS6Pltqo_clNES-NtXZrbaOWdaUtXtdGiafO6CifoIDNFcKe7eoxeH-5Xsyc8Xzw-z-7m2DIZt9iATImggiWCpyo2ljAwKec0ziBLFWOGK0LjdJ1YZYUwlDunQGWOgyJWWHaMLsfcxtfvnQutLvNgXVGYytVd0FQqxhMpuOjRiz_opu581X83UJwD6830FB0p6-sQvMt04_PS-K0moAeXenSpe5f6y6Uels530d26dOnPyre8HmAjEPpR9eb87-1_Yj8BWQV8cg</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>Weiss, Mia C.</creator><creator>Van Tine, Brian A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TO</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8457-0523</orcidid></search><sort><creationdate>20230301</creationdate><title>Relapsed Synovial Sarcoma: Treatment Options</title><author>Weiss, Mia C. ; Van Tine, Brian A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Chemotherapy</topic><topic>Clinical trials</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Oncology</topic><topic>Sarcoma</topic><topic>Sarcoma (SH Okuno</topic><topic>Sarcoma, Synovial - diagnosis</topic><topic>Sarcoma, Synovial - therapy</topic><topic>Section Editor</topic><topic>Soft Tissue Neoplasms</topic><topic>Soft tissue sarcoma</topic><topic>Synovial sarcoma</topic><topic>Topical Collection on Sarcoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weiss, Mia C.</creatorcontrib><creatorcontrib>Van Tine, Brian A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Current treatment options in oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weiss, Mia C.</au><au>Van Tine, Brian A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relapsed Synovial Sarcoma: Treatment Options</atitle><jtitle>Current treatment options in oncology</jtitle><stitle>Curr. Treat. Options in Oncol</stitle><addtitle>Curr Treat Options Oncol</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>24</volume><issue>3</issue><spage>229</spage><epage>239</epage><pages>229-239</pages><issn>1527-2729</issn><eissn>1534-6277</eissn><eissn>1534-5277</eissn><abstract>Opinion statement Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are currently standard of care, our fundamental understanding of the biology of SS is driving new therapies. We will review the current standard of care, as well as the current therapies showing promise in a clinical trial. It is our hope that by encouraging participation in clinical trials, the fundamental therapies available for SS will change the current treatment paradigm.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>36867389</pmid><doi>10.1007/s11864-023-01056-5</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-8457-0523</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1527-2729
ispartof Current treatment options in oncology, 2023-03, Vol.24 (3), p.229-239
issn 1527-2729
1534-6277
1534-5277
language eng
recordid cdi_proquest_miscellaneous_2783497646
source Springer Link
subjects Chemotherapy
Clinical trials
Humans
Medicine
Medicine & Public Health
Oncology
Sarcoma
Sarcoma (SH Okuno
Sarcoma, Synovial - diagnosis
Sarcoma, Synovial - therapy
Section Editor
Soft Tissue Neoplasms
Soft tissue sarcoma
Synovial sarcoma
Topical Collection on Sarcoma
title Relapsed Synovial Sarcoma: Treatment Options
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T10%3A59%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relapsed%20Synovial%20Sarcoma:%20Treatment%20Options&rft.jtitle=Current%20treatment%20options%20in%20oncology&rft.au=Weiss,%20Mia%20C.&rft.date=2023-03-01&rft.volume=24&rft.issue=3&rft.spage=229&rft.epage=239&rft.pages=229-239&rft.issn=1527-2729&rft.eissn=1534-6277&rft_id=info:doi/10.1007/s11864-023-01056-5&rft_dat=%3Cproquest_cross%3E2783497646%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c375t-a07d16263964d85ac130ad4425f0fd833a48125db9c8c66a24ee808fe4081c6c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2784403105&rft_id=info:pmid/36867389&rfr_iscdi=true