Transition Metal‐Catalyzed C−H Functionalization Through Electrocatalysis

• Published in: ChemSusChem 2023-06, Vol.16 (12), p.e202202201-n/a
• Main Authors: Baroliya, Prabhat Kumar, Dhaker, Mukesh, Panja, Subir, Al‐Thabaiti, Shaeel Ahmed, Albukhari, Soha M., Alsulami, Qana A., Dutta, Arnab, Maiti, Debabrata
• Format: Article
• Language: English
• Subjects: Chemical reactions; Cost effectiveness; C−H functionalization; electrochemistry; electrosynthesis; homogeneous catalysis; Oxidation; Oxidizing agents; Transition metals
• ISSN: 1864-5631; 1864-564X
• DOI: 10.1002/cssc.202202201

Electrochemically promoted transition metal‐catalyzed C−H functionalization has emerged as a promising area of research over the last few decades. However, development in this field is still at an early stage compared to traditional functionalization reactions using chemical‐based oxidizing agents. Recent reports have shown increased attention on electrochemically promoted metal‐catalyzed C−H functionalization. From the standpoint of sustainability, environmental friendliness, and cost effectiveness, electrochemically promoted oxidation of a metal catalyst offers a mild, efficient, and atom‐economical alternative to traditional chemical oxidants. This Review discusses advances in the field of transition metal‐electrocatalyzed C−H functionalization over the past decade and describes how the unique features of electricity enable metal‐catalyzed C−H functionalization in an economic and sustainable way. Merging transition metal catalysis with electrochemical oxidation has emerged as a potential catalyst system for C−H bond functionalization, avoiding the use of chemical‐based oxidants. Electrochemically promoted electrooxidation of the metal catalyst offers a mild, efficient and atom‐economical alternative to traditional chemical oxidant‐based systems. This Review highlights recent advances in transition metal‐electrocatalyzed C−H functionalization reactions.