The Spectrum of Thyroid Function Tests and Autoantibodies During Hospitalization and After Six Months of Discharge in COVID-19 Patients: Does COVID-19 Trigger Autoimmunity?

The aim of the study was to investigate thyroid function test (TFT) results and anti-thyroid antibody titers in acutely infected COVID-19 patients, as well as the changes in TFT and autoantibody results during the 6-months recovery period among survivors. A total of 163 adult COVID-19 patients and 1...

Full description

Saved in:
Bibliographic Details
Published in:Endocrine research 2023-07, Vol.48 (2-3), p.44-54
Main Authors: Alphan Uc, Ziynet, Yagcı, Pinar, Adibelli, Zelal, Duran, Cevdet
Format: Article
Language:English
Subjects:
Adult
Aftercare
Autoantibodies
Autoimmunity
COVID-19
Hospitalization
Humans
Hypothyroidism
Patient Discharge
post-recovery
Thyroid Diseases
Thyroid Function Tests
thyroid functional status
Thyrotropin
Thyroxine
Triiodothyronine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of the study was to investigate thyroid function test (TFT) results and anti-thyroid antibody titers in acutely infected COVID-19 patients, as well as the changes in TFT and autoantibody results during the 6-months recovery period among survivors. A total of 163 adult COVID-19 patients and 124 COVID-19 survivors were evaluated in terms of TFT (thyroid stimulating hormone [TSH], free triiodothyronine [fT3], and free thyroxine [fT4]) and anti-thyroid antibodies (anti-thyroglobulin [anti-Tg] and anti-thyroid peroxidase [anti-TPO]). Thyroid dysfunction was noted in 56.4% of patients on admission, including the non-thyroidal illness syndrome (NTIS) in most cases. Presence vs. absence of thyroid dysfunction on admission was associated with significantly higher rate of severe disease (p 
ISSN:0743-5800
1532-4206
DOI:10.1080/07435800.2023.2188086