Multiple surface properties of worn RGP lenses and adhesion of \+i\Pseudomonas aeruginosa.\-i

Rigid gas-permeable (RGP) lenses were collected after 10 days wear, 50 days wear and after end-stage use and an assessment was made of the surface properties that could influence the adhesion of Pseudomonas aeruginosa. Multiple regression analysis showed that both physical and chemical properties we...

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Bibliographic Details
Published in:Biomaterials 2003-01, Vol.24 (9), p.1663-70.
Main Authors: Bruinsma, G M, Rustema-Abbing, M, de Vries, J, Busscher, H J, van der Linden, M. L., Hooymans, J M M, van der Mei, H. C.
Format: Article
Language:English
Online Access:Get full text
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Summary:Rigid gas-permeable (RGP) lenses were collected after 10 days wear, 50 days wear and after end-stage use and an assessment was made of the surface properties that could influence the adhesion of Pseudomonas aeruginosa. Multiple regression analysis showed that both physical and chemical properties were predictive for the initial bacterial deposition on lens surfaces. After 10 days wear, bacterial deposition was governed by water contact angle, surface roughness, %O, %N and %Si while, after 50 days wear, surface roughness, %N and %Si were predictive for bacterial deposition. Initial bacterial deposition to end-stage lenses was solely dependent on surface roughness. Thus, although physico-chemical surface properties change with wear over days 10-50, the increased surface roughness of end-stage lenses is responsible for increased bacterial adhesion.
ISSN:0142-9612