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Scale-Up of Photochemical Reactions: Transitioning from Lab Scale to Industrial Production

In the past two decades, we have witnessed a rapid emergence of new and powerful photochemical and photocatalytic synthetic methods. Although these methods have been used mostly on a small scale, there is a growing need for efficient scale-up of photochemistry in the chemical industry. This review s...

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Bibliographic Details
Published in:Annual review of chemical and biomolecular engineering 2023-06, Vol.14 (1), p.283-300
Main Authors: Zondag, Stefan D.A, Mazzarella, Daniele, Noël, Timothy
Format: Article
Language:English
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Summary:In the past two decades, we have witnessed a rapid emergence of new and powerful photochemical and photocatalytic synthetic methods. Although these methods have been used mostly on a small scale, there is a growing need for efficient scale-up of photochemistry in the chemical industry. This review summarizes and contextualizes the advancements made in the past decade regarding the scale-up of photo-mediated synthetic transformations. Simple scale-up concepts and important fundamental photochemical laws have been provided along with a discussion concerning suitable reactor designs that should facilitate scale-up of this challenging class of organic reactions.
ISSN:1947-5438
1947-5446
DOI:10.1146/annurev-chembioeng-101121-074313