Quantitative analysis of lung parenchymal involvement in Behçet's disease by the novel automatic program

• Published in: International journal of rheumatic diseases 2023-05, Vol.26 (5), p.917-921
• Main Authors: Polat, Gökhan, Tezcan, Mehmet Alperen, Polat, Merve, Barutçugil, Furkan, Bayram, Tuncay, Sade, Recep, Kudaş, Özlem, Pirimoğlu, R. Berhan, İsmailova, Elshad, Yalçın, Ahmet, Meletlioğlu, Emrah, Kahraman, Mustafa
• Format: Article
• Language: English
• Subjects: Behcet Syndrome - diagnosis; Behcet's syndrome; Behçet's disease; Computed tomography; Humans; Lung; Lung Diseases; lung involvement; novel automatic program; Patients; Quantitative analysis; Tomography, X-Ray Computed; Vein & artery diseases
• ISSN: 1756-1841; 1756-185X
• DOI: 10.1111/1756-185X.14673

Objectives We aimed to quantitatively analyze lung parenchymal changes in Behçet's patients and to detect early parenchymal quantitative changes that occur in the absence of positive visual radiological findings. Methods In our study, a total of 31 patients with Behçet's disease, 17 with positive radiological findings and 14 patients without positive radiological findings, and a control group of 33 individuals were evaluated. The automatic program determined lung volumes, lung densities, and opacity volume percentages by evaluating the contrast‐enhanced lung computed tomography scans. Results The total lung volume was 3632.98 ± 1100.53 mL in the Behçet's disease patient group and 4925.70 ± 1098.88 mL in the control group, and there was a significant decrease in the total lung volume in Behçet's disease patients (P