Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals

• Published in: Journal of dentistry 2023-05, Vol.132, p.104480-104480, Article 104480
• Main Authors: Portes, Juliana, Bullón, Beatriz, Gallardo, Isabel, Fernandez-Riejos, Patricia, Quiles, Jose Luis, Giampieri, Francesca, Bullón, Pedro
• Format: Article
• Language: English
• Subjects: Aged; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - etiology; Humans; Lifestyle; Male; Periodontitis; Periodontitis - complications; Physical activity; Prediabetes; Prediabetic State - complications; Prediabetic State - diagnosis; Prediabetic State - epidemiology; Prevalence; Risk Factors; Type 2 diabetes mellitus; Western diet
• ISSN: 0300-5712; 1879-176X
• DOI: 10.1016/j.jdent.2023.104480

•The prevalence of diabetes mellitus type II and prediabetes is underestimated.•Lifestyle (negative habits, diet, and physical exercise) can directly impact the development of periodontitis and type II diabetes mellitus.•Detailed screening of patients in the dental office can help with the early diagnosis of these diseases or even their prevention. The prevalence of undiagnosed diabetes was estimated to increase with age and can reach 3.5%. The purpose of the study was to evaluate the prevalence of undiagnosed diabetes and prediabetes in the elderly patients who attended a dental clinic and to find common risk factors. Male patients, older than 50 years, attended their first dental visit to the School of Dentistry for a period of two years, and it was proposed to evaluate undiagnosed type 2 diabetes mellitus. Periodontal, biochemical, microbiological examinations, nutritional profile, and physical activity were performed. A total of 106 patients were examined, 6 (5.6%) had diabetes, and 37 (34.9%) had prediabetes without prior diagnosis. The severity of periodontitis was greater in patients with diabetes. Most of the patients were overweight and had increased systolic blood pressure. Patients with prediabetes and periodontitis had a low adherence to the Mediterranean diet. Tannerella forsythia was present in more patients with periodontitis, and the prevalence of Aggregatibacter actinomycetemcomitans is practically absent in groups with periodontitis, except for the group with diabetes. In the population studied, the prevalence of patients without a diagnosis of diabetes and prediabetes was very high and underestimated. The increased severity of periodontitis in patients with diabetes and in conjunction with the high level of cortisol seen in patients with periodontitis, especially those with diabetes, emphasize the dysregulation of the immunoinflammatory system. It is essential to add all this data to our dental practice to cover patient health with a broader landscape. Determinants directly related to the development of diabetes mellitus and periodontitis. [Display omitted]