Hydroxyapatite filled chitosan-polyacrylic acid polyelectrolyte complexes

Chitosan (CHI) has been complexed with polyacrylic acid (PAA) in the presence of hydroxyapatite (HAP) to prepare composites intended for bone substitute applications. Thermogravimetric analysis of the composite showed that the presence of HAP had little effect on the degradation profile of the polye...

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Bibliographic Details
Published in:Journal of materials science 2003-09, Vol.38 (17), p.3653-3662
Main Authors: SAILAJA, G. S, VELAYUDHAN, S, SUNNY, M. C, SREENIVASAN, K, VARMA, H. K, RAMESH, P
Format: Article
Language:English
Subjects:
Acrylics
Applied sciences
Biological and medical sciences
Biomedical materials
Chemical industry
Chitosan
Composites
Compressive strength
Degradation
Exact sciences and technology
Forms of application and semi-finished materials
Hydroxyapatite
Materials science
Medical sciences
Polyacrylic acid
Polyelectrolytes
Polymer industry, paints, wood
Polymer matrix composites
Substitute bone
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgical implants
Technology of polymers
Technology. Biomaterials. Equipments
Thermogravimetric analysis
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Summary:Chitosan (CHI) has been complexed with polyacrylic acid (PAA) in the presence of hydroxyapatite (HAP) to prepare composites intended for bone substitute applications. Thermogravimetric analysis of the composite showed that the presence of HAP had little effect on the degradation profile of the polyelectrolyte complex (PEC), except for the onset of degradation. Optimum compressive strength was observed for 70-weight percentage HAP filled PEC. The morphological analysis revealed that the HAP particles were uniformly distributed in the PEC matrix. The results indicate that HAP filled PEC of CHI and PAA could be prepared following the proposed simple route.
ISSN:0022-2461
1573-4803
DOI:10.1023/A:1025689701309