Dual-monomer molecularly imprinted electrochemical sensor based on amino-functionalized MOFs and graphene for trace determination of taurine

• Published in: Mikrochimica acta (1966) 2023-04, Vol.190 (4), p.162-162, Article 162
• Main Authors: Duan, Dingding, Wang, Jun, Han, Pengxin, Liu, Xin, Zhao, Luhang, Ma, Shenao
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Binding sites; Characterization and Evaluation of Materials; Chemical sensors; Chemistry; Chemistry and Materials Science; Dopamine; Electrodes; Graphene; Graphite; Graphite - chemistry; Humans; Iron; Limit of Detection; Microengineering; Molecular Imprinting; Monomers; Nanochemistry; Nanotechnology; Original Paper; Phenylenediamine; Sensors; Taurine
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-023-05751-w

A molecularly imprinted electrochemical sensor (MIECS) for trace determination of taurine was developed. The sensor was constructed by electropolymerizing dopamine and o-phenylenediamine as dual monomers on the surface of amino-functionalized iron-based MOFs and graphene composite-modified electrode. The porous structure and large specific surface area of amino-functionalized iron-based MOFs not only increase the number of imprinted sites, but also facilitate the binding of molecularly imprinted films. The presence of dual monomers can increase the binding sites during the formation of imprinted films. The linear range of this sensor for taurine detection is 1.00 × 10 −14 –1.00 × 10 −8  mol L −1 with a determination limit of 3.20 × 10 −15  mol L −1 . The proposed MIECS was successfully applied to quantify the amount of taurine in human serum sample with good recovery values from 97.3 to 113%. Graphical Abstract