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Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study
The aim of the study was to analyze the weaning success, the type of weaning procedures, and weaning duration in consecutive infants hospitalized in a pediatric intensive care unit over a winter season. A retrospective observational study was conducted in a pediatric intensive care unit in a tertiar...
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Published in: | Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2023-05, Vol.30 (4), p.201-205 |
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creator | Cassibba, J. Freycon, C. Doutau, J. Pin, I. Bellier, A. Fauroux, B. Mortamet, G. |
description | The aim of the study was to analyze the weaning success, the type of weaning procedures, and weaning duration in consecutive infants hospitalized in a pediatric intensive care unit over a winter season.
A retrospective observational study was conducted in a pediatric intensive care unit in a tertiary center. Infants hospitalized for severe bronchiolitis were included and the weaning procedure from continuous positive airway pressure (CPAP), noninvasive ventilation (NIV), or high-flow nasal cannula (HFNC) was analyzed.
Data from 95 infants (median age, 47 days) were analyzed. On admission, 26 (27%), 46 (49%), and 23 (24%) infants were supported with CPAP, NIV, and HFNC, respectively. Weaning failed in one (4%), nine (20%), and one (4%) infants while supported with CPAP, NIV, or HFNC, respectively (p = 0.1). In infants supported with CPAP, CPAP was stopped directly in five patients (19%) while HFNC was used as an intermediate ventilatory support in 21 (81%). The duration of weaning was shorter for HFNC (17 h, [IQR: 0–26]) than for CPAP (24 h, [14–40]) and NIV (28 h, [19–49]) (p |
doi_str_mv | 10.1016/j.arcped.2023.03.003 |
format | article |
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A retrospective observational study was conducted in a pediatric intensive care unit in a tertiary center. Infants hospitalized for severe bronchiolitis were included and the weaning procedure from continuous positive airway pressure (CPAP), noninvasive ventilation (NIV), or high-flow nasal cannula (HFNC) was analyzed.
Data from 95 infants (median age, 47 days) were analyzed. On admission, 26 (27%), 46 (49%), and 23 (24%) infants were supported with CPAP, NIV, and HFNC, respectively. Weaning failed in one (4%), nine (20%), and one (4%) infants while supported with CPAP, NIV, or HFNC, respectively (p = 0.1). In infants supported with CPAP, CPAP was stopped directly in five patients (19%) while HFNC was used as an intermediate ventilatory support in 21 (81%). The duration of weaning was shorter for HFNC (17 h, [IQR: 0–26]) than for CPAP (24 h, [14–40]) and NIV (28 h, [19–49]) (p < 0.01).
The weaning phase corresponds to a large proportion of noninvasive ventilatory support duration in infants with bronchiolitis. The weaning procedure following a “step-down” strategy may lead to an increase in the duration of weaning.</description><identifier>ISSN: 0929-693X</identifier><identifier>EISSN: 1769-664X</identifier><identifier>DOI: 10.1016/j.arcped.2023.03.003</identifier><identifier>PMID: 36990935</identifier><language>eng</language><publisher>France: Elsevier Masson SAS</publisher><subject>Acute respiratory failure ; Bronchiolitis - therapy ; Cannula ; Child ; Continuous Positive Airway Pressure ; Critically ill children ; Humans ; Infant ; Mechanical ventilation ; Noninvasive Ventilation ; Oxygen Inhalation Therapy ; Respiration, Artificial ; Weaning</subject><ispartof>Archives de pédiatrie : organe officiel de la Société française de pédiatrie, 2023-05, Vol.30 (4), p.201-205</ispartof><rights>2023 French Society of Pediatrics</rights><rights>Copyright © 2023 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-5ab90c6d70db0ddcbb7e2471ee9c4306cb23fd7362468d4b0d29823c976507073</citedby><cites>FETCH-LOGICAL-c408t-5ab90c6d70db0ddcbb7e2471ee9c4306cb23fd7362468d4b0d29823c976507073</cites><orcidid>0000-0003-0907-0315</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36990935$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cassibba, J.</creatorcontrib><creatorcontrib>Freycon, C.</creatorcontrib><creatorcontrib>Doutau, J.</creatorcontrib><creatorcontrib>Pin, I.</creatorcontrib><creatorcontrib>Bellier, A.</creatorcontrib><creatorcontrib>Fauroux, B.</creatorcontrib><creatorcontrib>Mortamet, G.</creatorcontrib><title>Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study</title><title>Archives de pédiatrie : organe officiel de la Société française de pédiatrie</title><addtitle>Arch Pediatr</addtitle><description>The aim of the study was to analyze the weaning success, the type of weaning procedures, and weaning duration in consecutive infants hospitalized in a pediatric intensive care unit over a winter season.
A retrospective observational study was conducted in a pediatric intensive care unit in a tertiary center. Infants hospitalized for severe bronchiolitis were included and the weaning procedure from continuous positive airway pressure (CPAP), noninvasive ventilation (NIV), or high-flow nasal cannula (HFNC) was analyzed.
Data from 95 infants (median age, 47 days) were analyzed. On admission, 26 (27%), 46 (49%), and 23 (24%) infants were supported with CPAP, NIV, and HFNC, respectively. Weaning failed in one (4%), nine (20%), and one (4%) infants while supported with CPAP, NIV, or HFNC, respectively (p = 0.1). In infants supported with CPAP, CPAP was stopped directly in five patients (19%) while HFNC was used as an intermediate ventilatory support in 21 (81%). The duration of weaning was shorter for HFNC (17 h, [IQR: 0–26]) than for CPAP (24 h, [14–40]) and NIV (28 h, [19–49]) (p < 0.01).
The weaning phase corresponds to a large proportion of noninvasive ventilatory support duration in infants with bronchiolitis. The weaning procedure following a “step-down” strategy may lead to an increase in the duration of weaning.</description><subject>Acute respiratory failure</subject><subject>Bronchiolitis - therapy</subject><subject>Cannula</subject><subject>Child</subject><subject>Continuous Positive Airway Pressure</subject><subject>Critically ill children</subject><subject>Humans</subject><subject>Infant</subject><subject>Mechanical ventilation</subject><subject>Noninvasive Ventilation</subject><subject>Oxygen Inhalation Therapy</subject><subject>Respiration, Artificial</subject><subject>Weaning</subject><issn>0929-693X</issn><issn>1769-664X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kMFq3DAQhkVpaTZp36AUHXvZ7VjySlYOhRCStBDopSG5CVkaN1q8kiPJDvv2VdjkWvhhBvTNDPoI-dLApoFGfN9tTLITug0DxjdQA_wdWTVSqLUQ7cN7sgLFaq_4wwk5zXkHAB10_CM54UIpUHy7Iv4eTfDhLx1S3NMQa7-Y7BekC4biR1NiOtA8T1NMhfpQM5hQMn325ZFmXDAh7VMM9tHH0Refz-lFoLHPmBZTfAxmpLnM7vCJfBjMmPHzaz0jd9dXfy5_rm9_3_y6vLhd2xa6st6aXoEVToLrwTnb9xJZKxtEZVsOwvaMD05ywVrRubYyTHWMWyXFFiRIfka-HfdOKT7NmIve-2xxHE3AOGfNZLUCrGm2FW2PqE0x54SDnpLfm3TQDegXyXqnj5L1i2QNNcDr2NfXC3O_r29vQ29WK_DjCGD95-Ix6Ww9BovOJ7RFu-j_f-EflAKR9w</recordid><startdate>202305</startdate><enddate>202305</enddate><creator>Cassibba, J.</creator><creator>Freycon, C.</creator><creator>Doutau, J.</creator><creator>Pin, I.</creator><creator>Bellier, A.</creator><creator>Fauroux, B.</creator><creator>Mortamet, G.</creator><general>Elsevier Masson SAS</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0907-0315</orcidid></search><sort><creationdate>202305</creationdate><title>Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study</title><author>Cassibba, J. ; Freycon, C. ; Doutau, J. ; Pin, I. ; Bellier, A. ; Fauroux, B. ; Mortamet, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-5ab90c6d70db0ddcbb7e2471ee9c4306cb23fd7362468d4b0d29823c976507073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acute respiratory failure</topic><topic>Bronchiolitis - therapy</topic><topic>Cannula</topic><topic>Child</topic><topic>Continuous Positive Airway Pressure</topic><topic>Critically ill children</topic><topic>Humans</topic><topic>Infant</topic><topic>Mechanical ventilation</topic><topic>Noninvasive Ventilation</topic><topic>Oxygen Inhalation Therapy</topic><topic>Respiration, Artificial</topic><topic>Weaning</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cassibba, J.</creatorcontrib><creatorcontrib>Freycon, C.</creatorcontrib><creatorcontrib>Doutau, J.</creatorcontrib><creatorcontrib>Pin, I.</creatorcontrib><creatorcontrib>Bellier, A.</creatorcontrib><creatorcontrib>Fauroux, B.</creatorcontrib><creatorcontrib>Mortamet, G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives de pédiatrie : organe officiel de la Société française de pédiatrie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cassibba, J.</au><au>Freycon, C.</au><au>Doutau, J.</au><au>Pin, I.</au><au>Bellier, A.</au><au>Fauroux, B.</au><au>Mortamet, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study</atitle><jtitle>Archives de pédiatrie : organe officiel de la Société française de pédiatrie</jtitle><addtitle>Arch Pediatr</addtitle><date>2023-05</date><risdate>2023</risdate><volume>30</volume><issue>4</issue><spage>201</spage><epage>205</epage><pages>201-205</pages><issn>0929-693X</issn><eissn>1769-664X</eissn><abstract>The aim of the study was to analyze the weaning success, the type of weaning procedures, and weaning duration in consecutive infants hospitalized in a pediatric intensive care unit over a winter season.
A retrospective observational study was conducted in a pediatric intensive care unit in a tertiary center. Infants hospitalized for severe bronchiolitis were included and the weaning procedure from continuous positive airway pressure (CPAP), noninvasive ventilation (NIV), or high-flow nasal cannula (HFNC) was analyzed.
Data from 95 infants (median age, 47 days) were analyzed. On admission, 26 (27%), 46 (49%), and 23 (24%) infants were supported with CPAP, NIV, and HFNC, respectively. Weaning failed in one (4%), nine (20%), and one (4%) infants while supported with CPAP, NIV, or HFNC, respectively (p = 0.1). In infants supported with CPAP, CPAP was stopped directly in five patients (19%) while HFNC was used as an intermediate ventilatory support in 21 (81%). The duration of weaning was shorter for HFNC (17 h, [IQR: 0–26]) than for CPAP (24 h, [14–40]) and NIV (28 h, [19–49]) (p < 0.01).
The weaning phase corresponds to a large proportion of noninvasive ventilatory support duration in infants with bronchiolitis. The weaning procedure following a “step-down” strategy may lead to an increase in the duration of weaning.</abstract><cop>France</cop><pub>Elsevier Masson SAS</pub><pmid>36990935</pmid><doi>10.1016/j.arcped.2023.03.003</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-0907-0315</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Acute respiratory failure Bronchiolitis - therapy Cannula Child Continuous Positive Airway Pressure Critically ill children Humans Infant Mechanical ventilation Noninvasive Ventilation Oxygen Inhalation Therapy Respiration, Artificial Weaning |
title | Weaning from noninvasive ventilatory support in infants with severe bronchiolitis: An observational study |
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