Association of activities of daily living and cognitive function with thickness of the upper extremity muscles in children and adults with cerebral palsy

• Published in: Journal of medical ultrasonics (2001) 2023-04, Vol.50 (2), p.245-252
• Main Authors: Masaki, Mitsuhiro, Uchikawa, Yuki, Iizuka, Yuka, Sugawara, Karin, Isobe, Honoka, Hattori, Fuyumi, Okamoto, Mami, Takahashi, Saki, Morohashi, Emina, Kitamura, Yuki
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Adult; Adults; Cerebral palsy; Cerebral Palsy - complications; Cerebral Palsy - diagnostic imaging; Child; Children; Cognition; Cognition & reasoning; Cognitive ability; Correlation analysis; Elbow; Evaluation; Humans; Imaging; Intelligence; Medicine; Medicine & Public Health; Muscle contraction; Muscle Spasticity - diagnostic imaging; Muscle strength; Muscle, Skeletal; Muscles; Original Article–orthopedics; Pediatrics; Radiology; Range of motion; Regression analysis; Spasticity; Thickness; Ultrasonic imaging; Ultrasound; Ultrasound imaging; Upper Extremity - diagnostic imaging
• ISSN: 1346-4523; 1613-2254
• DOI: 10.1007/s10396-023-01292-0

Purpose We examined the association of activities of daily living (ADL) and cognitive function with the upper extremity muscle thickness and upper extremity range of motion (ROM) and spasticity in children and adults with cerebral palsy (CP). Methods The subjects were 20 children and adults with CP. The ADL performed using the upper extremities and cognitive function were assessed using the self-care domain of the Pediatric Evaluation of Disability Inventory (PEDI) and the full-scale intelligence quotient (FSIQ) of the Wechsler Intelligence Scale for Children, fourth edition (WISC-IV), respectively. The WISC-IV was assessed in only seven of 20 subjects able to undergo evaluation. The thickness of the upper extremity muscles was measured using an ultrasound imaging device. Moreover, ROM and spasticity of the upper extremities were assessed using the Modified Ashworth Scale (MAS). Manual manipulation ability was also assessed using the Manual Ability Classification System (MACS). Results Stepwise regression analysis revealed that the extensor digitorum muscle thickness and MACS level were significant and independent factors of self-care in the PEDI. Partial correlation analysis with MACS level and age as control variables showed that the FSIQ of the WISC-IV was significantly associated with the thickness of the anterior fibers of the deltoid and flexor digitorum superficialis muscles. Conclusion Reduced ADL performed using the upper extremities is associated with decreased extensor digitorum muscle thickness rather than ROM and spasticity of the upper extremities in children and adults with CP.