Preoperative n-BCA embolization in the resection of submandibular lymphatic malformations refractory to sclerotherapy treatment: A pilot case series

Lymphatic malformations in the submandibular neck pose unique challenges to treatment that elevate their risk of recurrence. This case series provides a review of five patients, previously treated with sclerotherapy or with a history of multiple infections, who were treated in a novel fashion: singl...

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Bibliographic Details
Published in:International journal of pediatric otorhinolaryngology 2023-05, Vol.168, p.111510-111510, Article 111510
Main Authors: Shum, Axel, Beydoun, Ahmed Sam, Khalifee, Elie, Carlberg, Valerie, Plunk, Matthew, Chun, Robert
Format: Article
Language:English
Subjects:
Case series
Embolization, Therapeutic - methods
Enbucrilate - therapeutic use
Glue embolization
Humans
Lymphatic Abnormalities - diagnostic imaging
Lymphatic Abnormalities - surgery
Lymphatic malformation
n-BCA
Neck - pathology
Resection
Retrospective Studies
Sclerotherapy - methods
Single stage
Treatment Outcome
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Description
Summary:Lymphatic malformations in the submandibular neck pose unique challenges to treatment that elevate their risk of recurrence. This case series provides a review of five patients, previously treated with sclerotherapy or with a history of multiple infections, who were treated in a novel fashion: single-stage resection using preoperative n-butyl cyanoacrylate (n-BCA) glue embolization. We performed a retrospective medical record review of five patients who underwent single-stage n-BCA embolization by Interventional Radiology followed by surgical resection by Otolaryngology, including a review of their symptoms, previous treatments, and post-treatment surveillance, with follow-up ranging from 4 to 24 months after the treatment of interest. All study subjects had unremarkable perioperative courses, and four patients did not demonstrate any evidence of disease recurrence or persistence during the follow-up period. One patient was found to have a small area of persistent disease on post-treatment imaging, but has remained symptom free. Treatment of submandibular lymphatic malformations with n-BCA embolization followed by surgical resection can be performed in a single stage. This case series demonstrates that this approach can yield durable relief of symptoms, even in patients whose lesions were refractory to previous treatments.
ISSN:0165-5876
1872-8464
DOI:10.1016/j.ijporl.2023.111510