Bacteriological profile of the nasopharynx in patients with type 2 diabetes

• Published in: Annals of Agricultural and Environmental Medicine 2023-03, Vol.30 (1), p.183-189
• Main Authors: Mizgała-Izworska, Elżbieta, Żywiec, Joanna, Klekotka, Renata, Lukas, Witold
• Format: Article
• Language: English
• Subjects: Bacteria - genetics; Diabetes Mellitus, Type 2; Humans; Nasopharynx; Pharynx - microbiology; Staphylococcus aureus - genetics
• ISSN: 1232-1966; 1898-2263
• DOI: 10.26444/aaem/158024

Caring for people with diabetes is a challenge for doctors. GPs should be diagnostically vigilant and pay attention even to unusual symptoms reported by the patient, as they can progress quickly, impeding effective treatment. Targeted treatment of the bacteriological infection improves the prognosis in this group of patients. Its condition is to perform bacteriological tests. Statistics show that the infectious flora differ between people with diabetes and the general population. The aim of the study was to evaluate in a group of patients with type 2 diabetes without symptoms of active infection, the following: 1) composition of microflora in the nasal cavity and throat, with particular emphasis on the frequency and type of opportunistic and pathogenic microorganisms; 2) carrier status of Staphylococcus aureus bacteria in the nose, and its relationship to diabetes control/ other comorbidities predisposing to immuno-suppression. The study included 88 patients diagnosed with type 2 diabetes who were interviewed in the form of a questionnaire. Patients with additional systemic diseases and taking antibiotics within the last 6 weeks were excluded from the study. Microbiological tests required the collection of nasal and throat swabs from all enrolled patients. The bacteriological analysis included 176 nasal and throat swabs taken from 88 patients with type 2 diabetes. A total of 627 species of microorganisms were identified, and 90 potentially pathogenic strains present in the nasal cavity and throat of the subjects were isolated and identified. People with type 2 diabetes who do not show symptoms of infection are often carriers of potentially pathogenic bacteria in the nasopharynx.