Obstructive Sleep Apnea Patients with Atrial Arrhythmias Suffer from Prolonged Recovery from Desaturations

Objective: We aimed to investigate how acute and long-term effects of atrial arrhythmias affect the desaturation severity and characteristics determined from the oxygen saturation signal in OSA patients. Methods: 520 suspected OSA patients were included in retrospective analyses. Eight desaturation...

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Bibliographic Details
Published in:IEEE transactions on biomedical engineering 2023-07, Vol.70 (7), p.1-9
Main Authors: Rissanen, Marika, Korkalainen, Henri, Duce, Brett, Sillanmaki, Saara, Pitkanen, Henna, Suni, Aaron, Nikkonen, Sami, Kulkas, Antti, Toyras, Juha, Leppanen, Timo, Kainulainen, Samu
Format: Article
Language:English
Subjects:
Apnea
Arrhythmia
Atrial Arrhythmias
Atrial Fibrillation - diagnosis
Australia
Cardiac arrhythmia
Desaturation
Diagnosis
Distribution functions
Empirical analysis
Hospitals
Humans
Indexes
Intermittent Hypoxemia
Long-term effects
Obstructive Sleep Apnea
Oxygen
Oxygen content
Oxygen Saturation
Parameters
Polysomnography
Recording
Recovery
Retrospective Studies
Rhythm
Saturation
Signal Analysis
Sleep apnea
Sleep Apnea, Obstructive - diagnosis
Sleep disorders
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Summary:Objective: We aimed to investigate how acute and long-term effects of atrial arrhythmias affect the desaturation severity and characteristics determined from the oxygen saturation signal in OSA patients. Methods: 520 suspected OSA patients were included in retrospective analyses. Eight desaturation area and slope parameters were calculated from blood oxygen saturation signals recorded during polysomnographic recordings. Patients were grouped based on whether they had previously diagnosed atrial arrhythmia (i.e., atrial fibrillation (AFib) or atrial flutter) or not. Furthermore, patients with a previous atrial arrhythmia diagnosis were sub-grouped based on whether they had continuous AFib or sinus rhythm during the polysomnographic recordings. Empirical cumulative distribution functions and linear mixed models were utilized to investigate the connection between diagnosed atrial arrhythmia and the desaturation characteristics. Results: Patients with previous atrial arrhythmia diagnosis had greater desaturation recovery area when the 100% oxygen saturation baseline reference was considered (β=0.150-0.127, p ≤0.039) and more gradual recovery slopes (β=-0.181- -0.199, p
ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.2023.3236680