Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs

Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella ad...

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Bibliographic Details
Published in:Ecotoxicology (London) 2023-04, Vol.32 (3), p.309-320
Main Authors: Pérez-Iglesias, J. M., Natale, G. S., Brodeur, J. C., Larramendy, M. L.
Format: Article
Language:English
Subjects:
Adults
Amphibians
Amphibiotic species
Animals
Anura
Aquatic reptiles
Bioassays
Biological markers
Biomarkers
Body condition
Cereal crops
Cholinesterase
Cytogenetics
Damage
Deoxyribonucleic acid
DNA
DNA damage
Earth and Environmental Science
Ecology
Ecotoxicology
Environment
Environmental Management
Enzymes
Exposure
Foliar applications
Frogs
Genetic engineering
Glutathione
Glutathione transferase
Herbicides
Herbicides - toxicity
Larva
Micronuclei
Organisms
Pesticides
Pesticides - toxicity
Physiology
Reptiles & amphibians
Runoff
Skin
Soybean
Soybeans
Vertebrates
Water Pollutants, Chemical - toxicity
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Summary:Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella adults. Frogs were exposed to imazethapyr-based formulation Pivot ® H (10.59%) at concentrations representing possible acute routes: field runoff (S1:10 mg.L −1 ), exposure after direct foliar application (S2:100 mg.L −1 ) and during direct foliar application (S3:1000 mg.L −1 ). Post-exposure, endpoints levels were evaluated: organism alterations, biochemical activities and cytogenetic assays. Forty-eight hours post-exposure, antioxidant enzymes decrease, micronuclei induction and DNA damage were observed in all scenarios, while cholinesterase activity increase and body condition reduction were observed in frog-exposed to S3. Ninety-six hours post-exposure, frogs showed glutathione-S-transferase inhibition in S1, micronuclei induction in S2 and S3, and DNA-damage increase in S3. Herbicides routes of exposures in real-life could indicate that authorized applications have a risk to amphibian populations.
ISSN:0963-9292
1573-3017
DOI:10.1007/s10646-023-02639-6