Evaluation of peripheral anterior synechia formation following gonioscopy-assisted transluminal trabeculotomy surgery

Purpose To quantitatively assess the development of peripheral anterior synechia (PAS) formation rate and PAS locations on gonioscopic examination following gonioscopy-assisted transluminal trabeculotomy (GATT) surgery and investigate the surgical outcomes. Methods A total of 35 eyes from 31 patient...

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Bibliographic Details
Published in:International ophthalmology 2023-09, Vol.43 (9), p.3045-3053
Main Authors: Gunay, Murat, Turk, Adem, Ozturk, Hilal, Bulanik, Fatma Tugba, Uzlu, Dilek
Format: Article
Language:English
Subjects:
Corneal Diseases - surgery
Follow-Up Studies
Glaucoma
Glaucoma, Open-Angle - diagnosis
Glaucoma, Open-Angle - surgery
Gonioscopy
Humans
Intraocular Pressure
Iris Diseases - surgery
Medicine
Medicine & Public Health
Ophthalmology
Original Paper
Quadrants
Retrospective Studies
Surgery
Surgical outcomes
Trabeculectomy - adverse effects
Treatment Outcome
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Summary:Purpose To quantitatively assess the development of peripheral anterior synechia (PAS) formation rate and PAS locations on gonioscopic examination following gonioscopy-assisted transluminal trabeculotomy (GATT) surgery and investigate the surgical outcomes. Methods A total of 35 eyes from 31 patients with open angle glaucoma who underwent GATT or combined GATT and phacoemulsification surgery were analyzed. Presence of PAS was assessed on gonioscopy in nasal, temporal, superior and inferior quadrants at months 1, 3 and 6 following surgery. Surgical outcomes were also noted. Results Frequencies of PAS formation were 38.3%, 25.3%, 17.0% and 19.1% at postoperative 1 month, 34.0%, 26.4%, 17% and 22.6% at postoperative 3 months and 32.3%, 25.8%, 16.1% and 25.8% at postoperative 6 months, in nasal, temporal, superior and inferior quadrants, respectively. The highest amount of PAS involvement was 3 clock hours in the study which was identified only in nasal and inferior quadrants. Frequency of PAS formation did not significantly differ between nasal, temporal, superior and inferior quadrants at all time points ( p  > 0.05). No significant differences of mean IOP levels were observed between patients who developed PAS and who did not develop PAS at postoperative 1 month ( p  = 0.72), 3 months ( p  = 0.21) and 6 months ( p  = 0.59). The mean IOP and mean number of antiglaucoma medications decreased from 31.5 ± 7.2 mmHg and 3.6 ± 0.6 at baseline to 13.8 ± 3.1 mmHg and 1.6 ± 1.3 at postoperative 6 months, respectively ( p  
ISSN:1573-2630
0165-5701
1573-2630
DOI:10.1007/s10792-023-02704-3