Health state utility values in patients undergoing chest masculinization surgery

Chest masculinization surgery is the most common gender-affirming procedure performed in transgender and gender-diverse individuals. While evidence on the health-related quality of life (HRQL) impact of chest masculinization is starting to emerge, data on health state utility values (HSUVs) associat...

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Published in:Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2023-06, Vol.81, p.26-33
Main Authors: Kaur, Manraj N., Gallo, Lucas, Wang, Yi, Rae, Charlene, McEvenue, Giancarlo, Semple, John, Johnson, Natasha, Savard, Kinusan, Pusic, Andrea L., Coon, Devin, Klassen, Anne F.
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Language:English
Subjects:
Adult
BODY-Q
Chest masculinization
Depression
EQ-5D
Health Status
Humans
Pain
Patient-reported outcome measures
Quality of Life
Regression Analysis
Surveys and Questionnaires
Thoracic Surgical Procedures
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container_end_page 33
container_issue
container_start_page 26
container_title Journal of plastic, reconstructive & aesthetic surgery
container_volume 81
creator Kaur, Manraj N.
Gallo, Lucas
Wang, Yi
Rae, Charlene
McEvenue, Giancarlo
Semple, John
Johnson, Natasha
Savard, Kinusan
Pusic, Andrea L.
Coon, Devin
Klassen, Anne F.
description Chest masculinization surgery is the most common gender-affirming procedure performed in transgender and gender-diverse individuals. While evidence on the health-related quality of life (HRQL) impact of chest masculinization is starting to emerge, data on health state utility values (HSUVs) associated with the surgery is largely missing. The objectives of this study were to estimate the HSUVs using EQ-5D for patients seeking chest masculinization surgery and assess the determinants of EQ-5D score at 6 months postoperatively. Patients seeking chest masculinization at a single community plastic surgery clinic by 2 surgeons completed 3 patient-reported outcome measures – EQ-5D-3L, Patient Health Questionnaire (PHQ)-9, and BODY-Q Chest module – preoperatively and postoperatively at 6 weeks and 6-months. Friedman test was used to assess the differences in PROM scores at the 3 timepoints. Simple and backward stepwise regression analyses of 6-month postoperative EQ-5D scores were performed. A total of 113 patients (mean [SD] age, 25.7 [6.9] years) were included. The mean [SD] EQ-5D scores at preoperative, postoperative 6 weeks and 6 months were 0.81 [0.15], 0.84 [0.15] and 0.87 [0.12], respectively. Postoperatively, problems were most frequently reported in the dimensions “pain/discomfort” and “anxiety/depression". Preoperative PHQ-9 score was a predictor of 6-month postoperative EQ-5D scores following simple (p 
doi_str_mv 10.1016/j.bjps.2023.02.004
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While evidence on the health-related quality of life (HRQL) impact of chest masculinization is starting to emerge, data on health state utility values (HSUVs) associated with the surgery is largely missing. The objectives of this study were to estimate the HSUVs using EQ-5D for patients seeking chest masculinization surgery and assess the determinants of EQ-5D score at 6 months postoperatively. Patients seeking chest masculinization at a single community plastic surgery clinic by 2 surgeons completed 3 patient-reported outcome measures – EQ-5D-3L, Patient Health Questionnaire (PHQ)-9, and BODY-Q Chest module – preoperatively and postoperatively at 6 weeks and 6-months. Friedman test was used to assess the differences in PROM scores at the 3 timepoints. Simple and backward stepwise regression analyses of 6-month postoperative EQ-5D scores were performed. A total of 113 patients (mean [SD] age, 25.7 [6.9] years) were included. The mean [SD] EQ-5D scores at preoperative, postoperative 6 weeks and 6 months were 0.81 [0.15], 0.84 [0.15] and 0.87 [0.12], respectively. Postoperatively, problems were most frequently reported in the dimensions “pain/discomfort” and “anxiety/depression". Preoperative PHQ-9 score was a predictor of 6-month postoperative EQ-5D scores following simple (p &lt; 0.01) and backward stepwise linear regression analysis (p &lt; 0.01). Chest masculinization was associated with an improvement in overall HRL at 6 months postoperatively; however, this did not achieve statistical significance. Preoperative depression severity was a significant determinant of postoperative HRL. 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subjects Adult
BODY-Q
Chest masculinization
Depression
EQ-5D
Health Status
Humans
Pain
Patient-reported outcome measures
Quality of Life
Regression Analysis
Surveys and Questionnaires
Thoracic Surgical Procedures
title Health state utility values in patients undergoing chest masculinization surgery
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