In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes

The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the...

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Bibliographic Details
Published in:IEEE transactions on biomedical engineering 2005-09, Vol.52 (9), p.1612-1614
Main Authors: Cogan, S.F., Troyk, P.R., Ehrlich, J., Plante, T.D.
Format: Article
Language:English
Subjects:
Charge transfer
Charge-injection
current pulsing
Electric Impedance
Electric Stimulation - instrumentation
Electric Stimulation - methods
Electrodes
Equipment Design
Equipment Failure Analysis
Frequency
In vitro
Iridium - analysis
Iridium - chemistry
iridium oxide
microelectrode
Microelectrodes
neural stimulation
Oxidation
Platinum Compounds - analysis
Platinum Compounds - chemistry
platinum-iridium
Pulse shaping methods
Shafts
Shape control
Static Electricity
Voltage
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Summary:The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the interpulse period. Charge-injection limits were compared over a bias range of 0.1-0.7 V (versus Ag|AgCl) and pulse frequencies of 20, 50, and 100 Hz. The AIROF was capable of injecting between 4 and 10 times the charge of the PtIr electrode, with a maximum value of 3.9 mC/cm/sup 2/ obtained at a 0.7 V bias and 20 Hz frequency.
ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.2005.851503