Relationship between myocardial bridging and fatal ventricular arrhythmias in patients with hypertrophic cardiomyopathy: the HCM-MB study

• Published in: Herz 2023-10, Vol.48 (5), p.399-407
• Main Authors: Güner, Ahmet, Atmaca, Sezgin, Balaban, İsmail, Türkmen, İrem, Çeneli, Doğancan, Türkvatan, Aysel, Öner, Ender, Sürgit, Özgür, Güler, Arda, Uzun, Fatih, Babür Güler, Gamze, Kahraman, Serkan, Pala, Selçuk, Havan, Nuri, Yıldız, Mustafa, Ertürk, Mehmet
• Format: Article
• Language: English
• Subjects: Angiography; Arrhythmia; Cardiac arrhythmia; Cardiology; Cardiomyopathy; Computed tomography; Echocardiography; Health hazards; Heart; Internal Medicine; Medicine; Medicine & Public Health; Original Articles; Risk assessment; Risk factors; Tachycardia; Ventricle; Ventricular fibrillation
• ISSN: 0340-9937; 1615-6692
• DOI: 10.1007/s00059-023-05171-9

Background Myocardial bridging (MB) and hypertrophic cardiomyopathy (HCM) are associated with the risk of fatal ventricular arrhythmias (VAs). The goal of the study was to determine the relationship between MB and fatal VAs in HCM patients with implantable cardiac defibrillators (ICD). Methods A total of 108 HCM patients (mean age: 46.6 ± 13.6 years; male: 73) were enrolled in this retrospective study. All patients underwent transthoracic echocardiography and coronary computed tomography angiography. Fatal VAs including sustained ventricular tachycardia and ventricular fibrillation were documented in ICD records. Results There were documented fatal VAs in 29 (26.8%) patients during a mean follow-up time of 71.3 ± 30.9 months. Compared with the other groups, the fatal VA group had a higher incidence of the following: presence of MB (82.8 vs. 38%, p